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Relationship between Completion of Office-based Therapy Procedures for Convergence Insufficiency and Clinical Signs at Outcome

Kreifels, Kacie Marie

Abstract Details

2014, Master of Science, Ohio State University, Vision Science.
Background: The Convergence Insufficiency Treatment Trial (CITT) illustrated that office-based vergence/accommodative therapy (OBVAT) was the most effective treatment of symptomatic convergence insufficiency (CI). However, the effect of completing specific OBVAT procedures has not yet been investigated. Purpose: This study evaluated the relationship between completion of each phase 3 CITT OBVAT procedures and change in the clinical signs and symptoms of CI (CI Symptom Score, near point of convergence [NPC], positive fusional vergence [PFV], accommodative amplitude [AA], and accommodative facility [AF]) from baseline to outcome. Methods: This was a secondary analysis of data from children aged 9 to < 18 years with symptomatic CI (N=59) who were randomized to and completed the CITT OBVAT. Analysis of Covariance (ANCOVA) was performed to compare the relationship between completing each phase 3 therapy exercise and change from baseline to outcome in measures of the clinical signs and symptoms of CI (CISS score, NPC, PFV, AA, and AF) while controlling for baseline and parent-reported ADHD measures. In addition, this study utilized a Pearson chi-square analysis to investigate whether completion of each phase 3 therapy exercise was associated with treatment outcome (i.e. whether a patient was defined as a success, improved, or a non-responder). A two-sample t-test was used to test whether completion of the various phase 3 therapy exercises was related to the time it took to complete the precursor phase 1 and/or phase 2 exercises. Pearson chi-square analysis was used to explore the relationship between completion of phase 3 procedures and compliance with either in-office or home therapy. Power analysis was also performed to investigate the study’s ability to recognize clinically meaningful differences based on the small and asymmetric group sizes. Results: Completion of phase 3 computer orthoptics was related to significantly greater improvements in PFV (p=0.029) and completion of vectograms was related to significantly greater improvements in AF (p=0.026). Changes in CISS score, NPC and AA were not associated with completion of any phase 3 therapy procedure. Having parent-reported ADHD did not have an effect on the patient’s ability to complete any of the phase 3 procedures (p-values > 0.55). The time it took to complete a precursor phase 1 and/or phase 2 therapy technique was significantly related to completion of phase 3 for vectograms, aperture rule, and binocular accommodative facility (p = 0.029 for all comparisons). Conclusion: Completion of phase 3 office-based computer orthoptics may be significantly associated with greater improvement in PFV.
Marjean Kulp, OD, MS (Advisor)
G. Lynn Mitchell, MAS (Advisor)
Andrew Toole, OD, PhD (Committee Member)
Nicklaus Fogt, OD, PhD (Committee Member)
86 p.

Recommended Citations

Citations

  • Kreifels, K. M. (2014). Relationship between Completion of Office-based Therapy Procedures for Convergence Insufficiency and Clinical Signs at Outcome [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397772012

    APA Style (7th edition)

  • Kreifels, Kacie. Relationship between Completion of Office-based Therapy Procedures for Convergence Insufficiency and Clinical Signs at Outcome. 2014. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1397772012.

    MLA Style (8th edition)

  • Kreifels, Kacie. "Relationship between Completion of Office-based Therapy Procedures for Convergence Insufficiency and Clinical Signs at Outcome." Master's thesis, Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1397772012

    Chicago Manual of Style (17th edition)