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Prevalence of Oral Lesions in Patients with Inflammatory Bowel Disease

Kiyani, Amber

Abstract Details

2014, Master of Science, Ohio State University, Dentistry.
Abstract Introduction: Inflammatory bowel disease is a group of idiopathic conditions characterized by chronic inflammation of the gastrointestinal tract, with Crohns disease and ulcerative colitis being two common forms of this process. Extraintestinal manifestations of inflammatory bowel disease can be seen repeatedly in over 50% of patients, and can involve the skin, oral cavity, eyes, joints and the biliary tract. Oral lesions specific to Crohns disease and ulcerative colitis often have very characteristic appearances. Some non-specific processes such as aphthous ulceration and candidiasis have also been linked to this condition. Despite detailed documentation of the presence and the nature of oral lesions in patients with inflammatory bowel disease, limited data is available regarding the prevalence. The objective of this study was to estimate the frequency of oral changes associated with inflammatory bowel disease in the U.S population in comparison to age- and sex- matched healthy controls. Methodology: One hundred patients with a prior diagnosis of either Crohns disease or ulcerative colitis underwent periodic comprehensive oral examinations at the Wexner Medical Center gastroenterology clinic. Any abnormal oral mucosal changes noted during the exam were documented. A control population underwent a similar exam and documentation in the new patient screening clinic of The Ohio State University, College of Dentistry. Results: Out of 100 patients in the inflammatory bowel disease group, three were unavailable for follow-up. No lesions specific to either Crohns disease or ulcerative colitis were noted in the remaining ninety-seven patients over the 12-month period. Two patients presented with candidiasis, 2 with aphthous ulcers and 2 with herpetic lesions. One patient in the control group also presented with aphthous ulcers. Conclusion: Based on these findings, the prevalence of oral lesions in this patient population with inflammatory bowel disease can be estimated to be less than 1%.
Carl Allen (Advisor)
93 p.

Recommended Citations

Citations

  • Kiyani, A. (2014). Prevalence of Oral Lesions in Patients with Inflammatory Bowel Disease [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1402655058

    APA Style (7th edition)

  • Kiyani, Amber. Prevalence of Oral Lesions in Patients with Inflammatory Bowel Disease. 2014. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1402655058.

    MLA Style (8th edition)

  • Kiyani, Amber. "Prevalence of Oral Lesions in Patients with Inflammatory Bowel Disease." Master's thesis, Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1402655058

    Chicago Manual of Style (17th edition)