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A Comparison of the Therapeutic Effectiveness and Acceptance of Conventional Postural Drainage and Percussion, Intrapulmonary Percussive Ventilation and High Frequency Chest Wall Compression in Hospitalized Patients with Cystic Fibrosis

Varekojis, Sarah Meredith

Abstract Details

1998, Master of Science, Ohio State University, Allied Medical Professions.
A significant clinical manifestation of cystic fibrosis is abnormally abundant and viscous bronchial secretions. This leads to obstruction of bronchi in the lungs and predisposes the individual to chronic pulmonary infections. Bronchopulmonary hygiene is an essential part of the care of a patient with cystic fibrosis in order to enhance mucociliary clearance. Currently, several modalities of therapy are available, including high frequency chest wall compressions (HFCC), intrapulmonary percussive ventilation (IPV) and conventional postural drainage and percussion (PD&P). This study was designed to directly compare the sputum produced with HFCC, IPV and PD&P. Twenty-seven hospitalized patients were recruited for the study. Each patient received two consecutive days of each form of therapy in random order. All therapies were delivered three times a day for thirty minutes. Any sputum produced during the treatment time was expectorated and collected. Sputum was collected for a total of sixty minutes: fifteen minutes before the treatment during aerosol delivery, during the thirty minute treatment and for fifteen minutes post therapy. Sputum expectorated during each session was weighed wet and then dried and weighed again. The mean wet weight for HFCC was 4.95 (4.00) grams, IPV was 6.77 (5.77) grams and PD&P was 5.10 (5.56) grams. The mean dry weight for HFCC was 0.25 (0.17) grams, IPV was 0.38 (0.44) grams and PD&P was 0.33 (0.27) grams. Mean weights were analyzed using ANOVA with repeated measures. The mean wet sputum weight results approached statistical significance with p=0.050. The mean dry sputum weight results were not statistically significant with a p=0.140. Based on this study, it can be concluded that HFCC and IPV are at least as effective as conventional PD&P for the hospitalized patient with cystic fibrosis. The participants were also asked to complete a questionnaire regarding their feelings about the comfort, convenience, ease of use and efficacy of each of the modalities. The majority of respondents felt IPV and PD&P were somewhat or very comfortable, while they were divided on the comfort of HFCC. Almost all participants felt the three therapies were convenient and easy to use. PD&P and IPV were considered more effective than HFCC. The results of this study suggest that each patient needs to determine the correct balance of comfort, convenience, ease and efficacy for themselves when selecting a bronchopulmonary hygiene modality.
F. Herbert Douce (Advisor)
Phil Hoberty (Committee Member)
Karen McCoy (Committee Member)
52 p.

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Citations

  • Varekojis, S. M. (1998). A Comparison of the Therapeutic Effectiveness and Acceptance of Conventional Postural Drainage and Percussion, Intrapulmonary Percussive Ventilation and High Frequency Chest Wall Compression in Hospitalized Patients with Cystic Fibrosis [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1420644684

    APA Style (7th edition)

  • Varekojis, Sarah. A Comparison of the Therapeutic Effectiveness and Acceptance of Conventional Postural Drainage and Percussion, Intrapulmonary Percussive Ventilation and High Frequency Chest Wall Compression in Hospitalized Patients with Cystic Fibrosis. 1998. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1420644684.

    MLA Style (8th edition)

  • Varekojis, Sarah. "A Comparison of the Therapeutic Effectiveness and Acceptance of Conventional Postural Drainage and Percussion, Intrapulmonary Percussive Ventilation and High Frequency Chest Wall Compression in Hospitalized Patients with Cystic Fibrosis." Master's thesis, Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu1420644684

    Chicago Manual of Style (17th edition)