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Jingyan's Thesis-04-17-2015.pdf (18.4 MB)

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A Genome-wide Analysis to Identify and Characterize Novel Genes Involved in tRNA Biology in Saccharomyces cerevisiae

Wu, Jingyan
http://rave.ohiolink.edu/etdc/view?acc_num=osu1429197786

Abstract Details

2015, Doctor of Philosophy, Ohio State University, Plant Cellular and Molecular Biology.
Transfer ribonucleic acids (tRNAs) are essential molecules in all living cells, as they serve as the adapters that bring amino acids to ribosomes for protein synthesis. To identify all the missing gene products involved in tRNA biology, I conducted a systematic and unbiased genome-wide screen of nearly all annotated essential and unessential genes in budding yeast. I developed a rapid method for analyzing small RNAs from Saccharomyces cerevisiae wild-type and mutant cells from the deletion and temperature- sensitive collections.
Anita Hopper (Advisor)
Iris Meier (Committee Member)
Jane Jackman (Committee Member)
Keith Slotkin (Committee Member)
203 p.
Cellular Biology; Genetics; Molecular Biology
tRNA biogenesis, tRNA subcellular dynamics, tRNA processing, tRNA intron turnover, Xrn1, Rlg1, Crm1

Recommended Citations

Citations

  • Wu, J. (2015). A Genome-wide Analysis to Identify and Characterize Novel Genes Involved in tRNA Biology in Saccharomyces cerevisiae [Doctoral dissertation, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429197786

    APA Style (7th edition)

  • Wu, Jingyan. A Genome-wide Analysis to Identify and Characterize Novel Genes Involved in tRNA Biology in Saccharomyces cerevisiae. 2015. Ohio State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1429197786.

    MLA Style (8th edition)

  • Wu, Jingyan. "A Genome-wide Analysis to Identify and Characterize Novel Genes Involved in tRNA Biology in Saccharomyces cerevisiae." Doctoral dissertation, Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429197786

    Chicago Manual of Style (17th edition)

osu1429197786
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© 2015, some rights reserved.Creative Commons License A Genome-wide Analysis to Identify and Characterize Novel Genes Involved in tRNA Biology in Saccharomyces cerevisiae by Jingyan Wu is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by The Ohio State University and OhioLINK.