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Sensitivity Analyses of the Effect of Atomoxetine and Behavioral Therapy in a Randomized Control Trial

Nwosu, Ann
http://rave.ohiolink.edu/etdc/view?acc_num=osu1492475391440277

Abstract Details

2017, Master of Science, Ohio State University, Public Health.
Missing data is a common feature in longitudinal studies. The CHARTS study is randomized controlled trial of the effectiveness of atomoxetine and parent management training in reducing attention deficit/hyperactivity disorder symptoms of non-compliance and inattention in a population of children diagnosed with Autism Spectrum Disorder. During the ten-week trial period, several children were lost to follow-up, or were missing cognitive outcome data for various reasons. The cognitive data are analyzed from both an assumption of missing at random, and that of missing not at random. This paper will analyze the sensitivity of the data to departures from missing at random using the pattern-mixture factorization. Such an analysis strategy is structured to improve inference on the efficacy of the drug and behavioral intervention.
Rebecca Andridge (Advisor)
James Odei (Committee Member)
Biostatistics; Public Health
missing data atomoxetine RCT

Recommended Citations

Citations

  • Nwosu, A. (2017). Sensitivity Analyses of the Effect of Atomoxetine and Behavioral Therapy in a Randomized Control Trial [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492475391440277

    APA Style (7th edition)

  • Nwosu, Ann. Sensitivity Analyses of the Effect of Atomoxetine and Behavioral Therapy in a Randomized Control Trial. 2017. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1492475391440277.

    MLA Style (8th edition)

  • Nwosu, Ann. "Sensitivity Analyses of the Effect of Atomoxetine and Behavioral Therapy in a Randomized Control Trial." Master's thesis, Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492475391440277

    Chicago Manual of Style (17th edition)

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This open access ETD is published by The Ohio State University and OhioLINK.