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Multi-factorial intervention to increase adherence to oral appliance therapy for obstructive sleep apnea; A feasibility study

Maerz, Rachael Jean, Maerz

Abstract Details

2018, Master of Science, Ohio State University, Dentistry.
Objectives: Sleep apnea is a common chronic condition, with prevalence estimated at approximately 26% and 13% of adult males and females, respectively. The consequence of untreated OSA is increased morbidity and mortality. Long-term adherence to treatment for chronic conditions in developed countries is estimated at 50%. The aim of this study was to test whether a multifactorial intervention in addition to the standard of care increases adherence rates in patients using a titratable oral appliance to treat OSA. Methods: Subjects are between the ages of 18-60+, and have a diagnosis of OSA. After informed consent, they were assigned at random to the experimental or control group. A power analysis indicated group size of 30 subjects each was necessary to demonstrate a difference in the three variables (p<0.05) of +/- 15% between groups with a power of 0.86. The control group received routine care. Experimental subjects received in addition: educational material at scheduled intervals, spouse/partner packet, monthly follow up communication, communication with primary physician and dentist about patients, printouts of sensor data, and gift cards for timely follow up with sleep physician. Comparison of adherence was at 1-, 3-, and 6 month time points. Variables were: mean nights of appliance wear, mean nights adherent to prescribed wear time, mean nights worn per week, and the mean hours worn per night. Results: Forty subjects have been enrolled to date, 15 females and 25 males. Seventeen have been recorded at time point one (30 days). Seven subjects have left the study and there have been 5 sensor malfunctions (patients continuing to use appliance in the absence of objective monitoring). There were no significant differences between group for gender, age, and BMI at time point 1. There were no significant differences between groups for total nights worn, total nights adherent, number of nights/week, and hours/night for time points 1. Conclusions: The interventions were well received by the subjects, and most of the repeated interventions could be carried out by administrative personnel. There was a significant failure rate with the sensors that added a level of frustration to the process. There were no statistical differences for total nights worn, total nights adherent, number of nights/week, or hrs/night. This may be due to inadequate sample size. The means for all variables were higher in the experimental group compared with the control group.
Allen Firestone (Advisor)
50 p.

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Citations

  • Maerz, Maerz, R. J. (2018). Multi-factorial intervention to increase adherence to oral appliance therapy for obstructive sleep apnea; A feasibility study [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1522324879726596

    APA Style (7th edition)

  • Maerz, Maerz, Rachael. Multi-factorial intervention to increase adherence to oral appliance therapy for obstructive sleep apnea; A feasibility study . 2018. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1522324879726596.

    MLA Style (8th edition)

  • Maerz, Maerz, Rachael. "Multi-factorial intervention to increase adherence to oral appliance therapy for obstructive sleep apnea; A feasibility study ." Master's thesis, Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1522324879726596

    Chicago Manual of Style (17th edition)