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Sleep Loss and Environmental Exposures in Asthma Patients (SLEEAP): Chemical and Statistical Analyses for Interior Aerosols from Buffalo, NY Residences

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2018, Master of Science, Ohio State University, Civil Engineering.
We spend up to 90% of our time indoors and more than 30% of our time in the bedroom. Although aerosols and poor air quality most commonly occur outdoors, they can also occur inside the home and be very detrimental to health and sleep. The Ohio State University and the University of Buffalo are collaborating to determine how indoor exposure may be measured and to see how these pollutants contribute to asthma. In this study, 51 dust samples were retrieved from the bedroom doorframes of asthmatic adult women residing in Buffalo, New York. Six environmental standards were used to determine whether certain compounds, especially those related to combustion sources, can be found in the dust samples. Compounds in our standards include n-alkanes (C7-C40), PAHs, cholesterol, 5-alpha-cholestane, nicotine, and phthalates. The first five compounds and compound groups are associated with combustion, thereby allowing us to test the influence of combustion sources on indoor dust. We used Gas-Chromatography Mass-Spectrometry (GC-MS) to analyze our samples. We evaluated calibration curves and reviewed measures such as Limits of Detection (LOD) and Limits of Quantification (LOQ). We then picked twelve activities which we thought would lead to greater contributions of the chemicals we measured in the indoor aerosol. Using SAS (version 9.3), we tested for which compounds were significant based on a p-value and q-value less than 0.05. Nicotine was the only compound that was significant to all its associating activities. After the preliminary stage of this research, more work including new methods will be needed to further calculate compound significance, calculate compound concentration in samples, and to perform a source contribution.
Andrew May, Dr. (Advisor)
Karen Dannemiller, Dr. (Committee Member)
Jeffrey Bielicki, Dr. (Committee Member)
93 p.

Recommended Citations

Citations

  • Luma, J. (2018). Sleep Loss and Environmental Exposures in Asthma Patients (SLEEAP): Chemical and Statistical Analyses for Interior Aerosols from Buffalo, NY Residences [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523636175286216

    APA Style (7th edition)

  • Luma, Johnson. Sleep Loss and Environmental Exposures in Asthma Patients (SLEEAP): Chemical and Statistical Analyses for Interior Aerosols from Buffalo, NY Residences . 2018. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1523636175286216.

    MLA Style (8th edition)

  • Luma, Johnson. "Sleep Loss and Environmental Exposures in Asthma Patients (SLEEAP): Chemical and Statistical Analyses for Interior Aerosols from Buffalo, NY Residences ." Master's thesis, Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1523636175286216

    Chicago Manual of Style (17th edition)