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A Parametric Study of Physiological Changes to Develop a Finite Element Model of Disc Degeneration

Felon, Leonora A.
http://rave.ohiolink.edu/etdc/view?acc_num=toledo1290185215

Abstract Details

2010, Master of Science, University of Toledo, Bioengineering.
Finite Element spine models have been created to simulate disc degeneration in the past; however they have not taken into account physiology and how other levels are affected by a change at another level. Here in lies the problem with those models. Several models were created to explore how physiological changes change an experimental validated L3/S1 spine model. Physiological conditions taken into account included Poisson’s ratio of nucleus, tearing of the annulus and physiologically relevant compressive loads on the spine. Much was learned through this process and a final set of three models were created and biomechanically evaluated. The model with the greatest degeneration was also “graded” based on clinical grading schemes and studies. The model was capable of simulating motion similar to cadaver studies done by others. It showed increased pressure in the disc and loading on the facets as the model was farther degenerated. Finally, based on the clinical grading schemes and studies, the large degenerated disc model was determined to be a grade IV degeneration of the L4/5 disc.
Vijay Goel, PhD (Advisor)
Scott Molitor, PhD. (Committee Member)
Mohamed Hefzy, PhD (Committee Member)
143 p.
Finite Element; Spine; Disc degeneration

Recommended Citations

Citations

  • Felon, L. A. (2010). A Parametric Study of Physiological Changes to Develop a Finite Element Model of Disc Degeneration [Master's thesis, University of Toledo]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1290185215

    APA Style (7th edition)

  • Felon, Leonora. A Parametric Study of Physiological Changes to Develop a Finite Element Model of Disc Degeneration. 2010. University of Toledo, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=toledo1290185215.

    MLA Style (8th edition)

  • Felon, Leonora. "A Parametric Study of Physiological Changes to Develop a Finite Element Model of Disc Degeneration." Master's thesis, University of Toledo, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1290185215

    Chicago Manual of Style (17th edition)

toledo1290185215
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© 2010, all rights reserved.
This open access ETD is published by University of Toledo and OhioLINK.