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Release of Low Acyl Gellan Gum in a Controlled Release System

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2018, Master of Science, University of Toledo, Chemical Engineering.
The release of low acyl gellan gum from a controlled release system was evaluated at 0, 0.5, 1% concentration of tri-calcium phosphate. Release rates of 6.387, 0.345, and 0.679 mg/h of low acyl gellan gum were obtained for the 0, 0.5, and 1% tri-calcium phosphate, respectively. Additionally, rheological properties were obtained for the 0.5% TCP gel and 1% TCP. Moreover, low acyl gellan gum was enzymatically cleaved into two smaller molecular weight products, named midi-GAGR and mini-GAGR. Rheological testing revealed molecular weights of approximately 5,500 Da and 1,300 Da for midi-GAGR and mini-GAGR, respectively. Furthermore, the antioxidant capacities of both products were evaluated using DPPH assay. Midi-GAGR was able to scavenge 23% of free radicals, while mini-GAGR scavenged 13%. The polysaccharide low acyl gellan gum has shown promise to be engineered to fit clinical applications.
Dong-Shik Kim (Committee Chair)
Joshua Park (Committee Member)
Yakov Lapitsky (Committee Member)
53 p.

Recommended Citations

Citations

  • Baawad, A. (2018). Release of Low Acyl Gellan Gum in a Controlled Release System [Master's thesis, University of Toledo]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1544823979777171

    APA Style (7th edition)

  • Baawad, Abdullah. Release of Low Acyl Gellan Gum in a Controlled Release System. 2018. University of Toledo, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=toledo1544823979777171.

    MLA Style (8th edition)

  • Baawad, Abdullah. "Release of Low Acyl Gellan Gum in a Controlled Release System." Master's thesis, University of Toledo, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1544823979777171

    Chicago Manual of Style (17th edition)