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CORRELATES OF HEALTH-RELATED QUALITY OF LIFE IN EPILEPTIC AND PSYCHOGENIC NONEPILEPTIC SEIZURES: MOOD SYMPTOMS, PERSONALITY FACTORS, AND NEUROCOGNITIVE FUNCTIONING

TESTA, S. MARC

Abstract Details

2004, PhD, University of Cincinnati, Arts and Sciences : Psychology.
Individuals with psychogenic nonepileptic seizures (PNES) consistently rate their health-related quality of life (HRQOL) more poorly than those with epileptic seizures (ES). The current study investigated the impact of mood, personality factors, and neurocognitive functioning on the relationship between seizure diagnosis and HRQOL. A parallel goal of the current study was to inform treatment designed to improve HRQOL among individuals with intractable seizures. A total of 114 individuals (69 ES and 45 PNES) undergoing a comprehensive epilepsy evaluation completed the Quality of Life in Epilepsy-89 questionnaire, measures of current mood state, the Minnesota Multiphasic Personality Inventory-2, and a battery of neuropsychological tests. A series of hierarchical multiple regression analyses was conducted to determine the contribution of current mood state, personality, and neurocognitive functioning to HRQOL above and beyond seizure diagnosis in order to explain the reported between-group differences. Similar to previous studies, individuals with PNES reported poorer HRQOL than those with ES. Additionally, current mood state was strongly related to HRQOL and appeared to moderate the relationship between seizure diagnosis and HRQOL. However, when somatization and more chronic aspects of psychological distress were added to the model, the moderating role of current mood state no longer remained significant. Moreover, somatization and psychological distress were significantly related to HRQOL. Relationships between neurocognitive functioning and HRQOL were not detected. While current mood state accounted for a significant portion of HRQOL, treatments designed to improve HRQOL among individuals with intractable seizures should also address chronic psychological distress and mechanisms of coping.
Dr. Bruce Schefft (Advisor)
61 p.

Recommended Citations

Citations

  • TESTA, S. M. (2004). CORRELATES OF HEALTH-RELATED QUALITY OF LIFE IN EPILEPTIC AND PSYCHOGENIC NONEPILEPTIC SEIZURES: MOOD SYMPTOMS, PERSONALITY FACTORS, AND NEUROCOGNITIVE FUNCTIONING [Doctoral dissertation, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1092087452

    APA Style (7th edition)

  • TESTA, S. MARC. CORRELATES OF HEALTH-RELATED QUALITY OF LIFE IN EPILEPTIC AND PSYCHOGENIC NONEPILEPTIC SEIZURES: MOOD SYMPTOMS, PERSONALITY FACTORS, AND NEUROCOGNITIVE FUNCTIONING. 2004. University of Cincinnati, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1092087452.

    MLA Style (8th edition)

  • TESTA, S. MARC. "CORRELATES OF HEALTH-RELATED QUALITY OF LIFE IN EPILEPTIC AND PSYCHOGENIC NONEPILEPTIC SEIZURES: MOOD SYMPTOMS, PERSONALITY FACTORS, AND NEUROCOGNITIVE FUNCTIONING." Doctoral dissertation, University of Cincinnati, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1092087452

    Chicago Manual of Style (17th edition)