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POROUS INORGANIC SUPPORTED LIQUID MEMBRANES FOR USE IN ION CHANNELING

GLADDING, SARAH M

Abstract Details

2005, MS, University of Cincinnati, Engineering : Chemical Engineering.
The objective of this research was to use a porous inorganic material to support a biological membrane, which could be used in ion channeling. The support consisted of a gamma-alumina core covered with a thin silica layer. The hydrophilic surface of the silica was then modified with C18 (octadecyltrichlorosilane) in order to make the surface hydrophobic. A lipid layer was then deposited, in which the hydrophobic tails of the lipid layer interacted with the hydrophobic carbon chains of the C18 to create a bilayer, which served as a host for the protein, Gramicidin D. Experimental results show that the inorganic support did provide stability for the biomembrane, as well as provided a reservoir to store material for ion exchange. Ion exchange did occur, especially after the addition of the protein ion channels, and this exchange was measured using a pH change test.
Dr. Jerry Lin (Advisor)
86 p.

Recommended Citations

Citations

  • GLADDING, S. M. (2005). POROUS INORGANIC SUPPORTED LIQUID MEMBRANES FOR USE IN ION CHANNELING [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1109343185

    APA Style (7th edition)

  • GLADDING, SARAH. POROUS INORGANIC SUPPORTED LIQUID MEMBRANES FOR USE IN ION CHANNELING. 2005. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1109343185.

    MLA Style (8th edition)

  • GLADDING, SARAH. "POROUS INORGANIC SUPPORTED LIQUID MEMBRANES FOR USE IN ION CHANNELING." Master's thesis, University of Cincinnati, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1109343185

    Chicago Manual of Style (17th edition)