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ucin1131920589.pdf (2.78 MB)
ETD Abstract Container
Abstract Header
Developing Pulsatile Flow in a Deployed Coronary Stent
Author Info
Rajamohan, Divakar
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589
Abstract Details
Year and Degree
2005, MS, University of Cincinnati, Engineering : Mechanical Engineering.
Abstract
A major consequence of stent implantation is restenosis that occurs due to neointimal formation. Recent evidence suggests that there are several factors such as geometry and size of vessel, and stent design that alters hemodynamic parameters, including local wall shear stress distributions, which influence the progression of restenosis. The present three-dimensional analysis of developing pulsatile flow in a deployed coronary stent quantifies hemodynamic parameters and illustrates the changes in local wall shear stress distributions and their impact on restenosis. The present model mimics the worst possible scenario where the stent is placed at the entrance region of a branched coronary artery. The present results indicate that the immediate downstream of strut intersections are areas highly susceptible to restenosis whereas a high shear stress at the strut intersection may cause platelet activation and free emboli formation.
Committee
Dr. Rupak Banerjee (Advisor)
Pages
71 p.
Keywords
Coronary stent
;
restenosis
;
pulsatile
;
developing
;
wall shear stress
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Citations
Rajamohan, D. (2005).
Developing Pulsatile Flow in a Deployed Coronary Stent
[Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589
APA Style (7th edition)
Rajamohan, Divakar.
Developing Pulsatile Flow in a Deployed Coronary Stent.
2005. University of Cincinnati, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589.
MLA Style (8th edition)
Rajamohan, Divakar. "Developing Pulsatile Flow in a Deployed Coronary Stent." Master's thesis, University of Cincinnati, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589
Chicago Manual of Style (17th edition)
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Document number:
ucin1131920589
Download Count:
995
Copyright Info
© 2005, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.