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SERUM BIOMARKER AND ENVIRONMENTAL MEASURES OF FUNGAL EXPOSURE IN OCCUPANTS OF A WATER DAMAGED BUILDING AND ASSOCIATED HEALTH EFFECTS

THOMAS, GREGORY A
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1155180288

Abstract Details

2006, MS, University of Cincinnati, Medicine : Occupational Medicine.
The current study uses the cross-sectional design of a NIOSH health hazard evaluation of health complaints in a moldy water damaged building and evaluates both symptom prevalence and the use of a fungal-specific hemolysin, Stachylysin™, as a possible serum biomarker of internal fungal exposure. Results revealed that employees of two different employers occupying different parts of the fungal contaminated building reported higher rates of respiratory complaints than that of an off-site comparison group. In addition, one group of exposed workers had a much greater prevalence of symptoms than the other exposed group despite sharing different parts of the same workplace, possibly reflecting differences in exposure (differences in HVAC systems and building condition). Poor reproducibility of the Stachylysin™ assay, and poor correlation with environmental sampling measurements of exposure, suggest that measurement of serum Stachylysin™ in its present form may not be useful in investigations of Stachybotrys chartarum exposure.
Dr. Sue Ross (Advisor)
51 p.
stachybotrys chartarum; stachylysin; mold; water damaged building health effects

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Citations

  • THOMAS, G. A. (2006). SERUM BIOMARKER AND ENVIRONMENTAL MEASURES OF FUNGAL EXPOSURE IN OCCUPANTS OF A WATER DAMAGED BUILDING AND ASSOCIATED HEALTH EFFECTS [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1155180288

    APA Style (7th edition)

  • THOMAS, GREGORY. SERUM BIOMARKER AND ENVIRONMENTAL MEASURES OF FUNGAL EXPOSURE IN OCCUPANTS OF A WATER DAMAGED BUILDING AND ASSOCIATED HEALTH EFFECTS. 2006. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1155180288.

    MLA Style (8th edition)

  • THOMAS, GREGORY. "SERUM BIOMARKER AND ENVIRONMENTAL MEASURES OF FUNGAL EXPOSURE IN OCCUPANTS OF A WATER DAMAGED BUILDING AND ASSOCIATED HEALTH EFFECTS." Master's thesis, University of Cincinnati, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1155180288

    Chicago Manual of Style (17th edition)

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© 2006, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.