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Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers

Gaultney, Beverly Teal

Abstract Details

2010, MS, University of Cincinnati, Medicine : Industrial Hygiene (Environmental Health).
Polycyclic aromatic hydrocarbons (PAHs), which consist of 2 or more fused benzene rings, are formed by the incomplete combustion of fossil fuels. Although PAHs are an exposure concern in many industrial sectors, one industry of particular interest is the rubber industry. PAHs make up around 20% of the total weight of rubber products including tires. For tire manufacturing, PAH exposures arise when they are added as extender oils and they may also be present when carbon black is used to produce the master batch material (IARC, 1982). Such exposures have been of public health interest because epidemiology studies of workers exposed to PAHs have identified an increase risk of developing cancers of the lungs, urinary bladder, skin, and prostate (Bofetta et al 1997; Constantino et al 1995). Naphthalene is the simplest and most volatile member of the PAHs. The major route of elimination of naphthalene is via the formation of the hydroxylated metabolites 1- and 2- naphthol which are excreted through the urine (Onyemauwa et al 2009; Serdar et al 2004; Preuss et al 2003). The hypothesis of this thesis is that Post-shift urinary 2-naphthol levels are significantly higher than pre-shift urinary 2-naphthol levels in rubber workers exposed to naphthalene.
Glenn Talaska, PhD (Committee Chair)
Paul Succop, PhD (Committee Member)
Andrew Maier, PhD, MS (Committee Member)
36 p.

Recommended Citations

Citations

  • Gaultney, B. T. (2010). Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357

    APA Style (7th edition)

  • Gaultney, Beverly Teal. Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers. 2010. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357.

    MLA Style (8th edition)

  • Gaultney, Beverly Teal. "Determination of Urinary 2-Naphthol Concentration in Rubber Manufacturing Workers." Master's thesis, University of Cincinnati, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1266608357

    Chicago Manual of Style (17th edition)