Skip to Main Content
Frequently Asked Questions
Submit an ETD
Global Search Box
Need Help?
Keyword Search
Participating Institutions
Advanced Search
School Logo
Files
File List
3053.pdf (39.15 MB)
ETD Abstract Container
Abstract Header
Apolipoprotein A-IV Structural Determination and Biophysical Characterization
Author Info
Deng, Xiaodi A
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368085505
Abstract Details
Year and Degree
2013, PhD, University of Cincinnati, Medicine: Molecular Genetics, Biochemistry, and Microbiology.
Abstract
Apolipoproteins are key structural elements of lipoproteins and critical mediators of lipid metabolism. Their detergent-like properties allow them to emulsify lipids or exist lipid-free in various states of self-association. Part of this family is apolipoprotein (apo) A-IV, a 43 kDa lipid binding protein. Biologically, apoA-IV has been linked to a wide range of functions: reverse cholesterol transport, chylomicron secretion, protection against LDL oxidation, anti-inflammation, satiety signaling, and glucose metabolism. The aims below are designed to structurally characterize apoA-IV.
Committee
Thomas Thompson, Ph.D. (Committee Chair)
Sean Davidson, Ph.D. (Committee Member)
Gary Dean, Ph.D. (Committee Member)
Andrew Herr, Ph.D. (Committee Member)
Rhett Kovall, Ph.D. (Committee Member)
Pages
186 p.
Subject Headings
Biochemistry
;
Microbiology
;
Molecular Chemistry
Keywords
lipoproteins
;
mediators
;
lipid metabolism
Recommended Citations
Refworks
EndNote
RIS
Mendeley
Citations
Deng, X. A. (2013).
Apolipoprotein A-IV Structural Determination and Biophysical Characterization
[Doctoral dissertation, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368085505
APA Style (7th edition)
Deng, Xiaodi.
Apolipoprotein A-IV Structural Determination and Biophysical Characterization.
2013. University of Cincinnati, Doctoral dissertation.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368085505.
MLA Style (8th edition)
Deng, Xiaodi. "Apolipoprotein A-IV Structural Determination and Biophysical Characterization." Doctoral dissertation, University of Cincinnati, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1368085505
Chicago Manual of Style (17th edition)
Abstract Footer
Document number:
ucin1368085505
Download Count:
177
Copyright Info
© 2013, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.