Skip to Main Content
Frequently Asked Questions
Submit an ETD
Global Search Box
Need Help?
Keyword Search
Participating Institutions
Advanced Search
School Logo
Files
File List
12712.pdf (6.45 MB)
ETD Abstract Container
Abstract Header
Diagnosis of Coronary Artery Disease Using Pressure Drop Coefficient
Author Info
Kolli, Kranthi Kumar
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1415615529
Abstract Details
Year and Degree
2014, PhD, University of Cincinnati, Engineering and Applied Science: Mechanical Engineering.
Abstract
The coronary circulation is influenced by two well-recognized pathophysiological serial resistances: epicardial stenosis and microvascular dysfunction. The independent evaluation of true ischemic severity of epicardial coronary stenosis and diseased myocardium is a challenge to current clinical diagnostic protocols. With the recent development of miniaturized sensor technology, it is possible to calculate current established hemodynamic parameters e.g. Fractional Flow Reserve (FFR; pressure derived) and Coronary Flow Reserve (CFR; flow derived) with minimal-invasive clinical procedures, which showed a high agreement with non-invasive stress testing. However, an important limitation in using either of the above single modality technique is the limited differentiation they offer between hemodynamic influences exerted by epicardial stenosis and the microcirculation.
Committee
Rupak Banerjee, Ph.D P.E. (Committee Chair)
Mohamed Effat, M.D. (Committee Member)
Frank Gerner, Ph.D. (Committee Member)
Tarek Helmy, Ph.D. (Committee Member)
Michael Kazmierczak, Ph.D. (Committee Member)
Pages
150 p.
Subject Headings
Mechanical Engineering
Keywords
coronary artery disease
;
fractional flow reserve
;
pressure drop coefficeint
;
fluid dynamics
Recommended Citations
Refworks
EndNote
RIS
Mendeley
Citations
Kolli, K. K. (2014).
Diagnosis of Coronary Artery Disease Using Pressure Drop Coefficient
[Doctoral dissertation, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1415615529
APA Style (7th edition)
Kolli, Kranthi.
Diagnosis of Coronary Artery Disease Using Pressure Drop Coefficient.
2014. University of Cincinnati, Doctoral dissertation.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1415615529.
MLA Style (8th edition)
Kolli, Kranthi. "Diagnosis of Coronary Artery Disease Using Pressure Drop Coefficient." Doctoral dissertation, University of Cincinnati, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1415615529
Chicago Manual of Style (17th edition)
Abstract Footer
Document number:
ucin1415615529
Download Count:
626
Copyright Info
© 2014, some rights reserved.
Diagnosis of Coronary Artery Disease Using Pressure Drop Coefficient by Kranthi Kumar Kolli is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by University of Cincinnati and OhioLINK.