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Associated Symptoms of Chronic Migraine in Children and Adolescents

Kroner, John
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1427980899

Abstract Details

2015, MS, University of Cincinnati, Medicine: Epidemiology (Environmental Health).
Objective: To determine the phenotypical characteristics of migraine experienced by adolescents diagnosed with chronic migraine and to determine if behavioral treatment shown to reduce headache frequency also leads to changes in migraine characteristics. Background: There are no evidence based interventions for children and adolescents who suffer from chronic migraine. As part of a randomized clinical trial, subjects received Cognitive Behavioral Therapy plus Amitriptyline (CBT+A) or headache education and Amitriptyline (HE+A) to determine if CBT led to improved outcomes in headache frequency and disability. Methods: A total of 135 adolescents aged 10 to 17 diagnosed with chronic migraine (=15 headache days/month) and a Pediatric Migraine Disability Assessment Score (PedMIDAS) greater than 20 points were assigned to the CBT group (n = 64) or the headache education group (n = 71). During the treatment phase of the trial (20 weeks) subjects kept a daily dairy that recorded headache frequency and symptoms. Results: Subjects who received CBT+A had a greater reduction in headache frequency rate than subjects who received HE+A. There was no statistically significant difference between the groups in the proportion of associated migraine symptoms reported. Conclusions: CBT is an effective treatment showing greater improvement in headache frequency over twenty weeks compared to HE. However, the experience of migraine (i.e., the symptoms experienced) was not different between the groups. Subjects who received CBT+A had fewer reported headaches, but when they did have a headache, there was no phenotypical difference between the treatment groups.
Susan Pinney, Ph.D. (Committee Chair)
Scott Powers, Ph.D. A.B.P.P. (Committee Member)
Marepalli Rao, Ph.D. (Committee Member)
27 p.
Epidemiology
Chronic Migraine; Pediatric Migraine; Cognitive Behavioral Therapy

Recommended Citations

Citations

  • Kroner, J. (2015). Associated Symptoms of Chronic Migraine in Children and Adolescents [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1427980899

    APA Style (7th edition)

  • Kroner, John. Associated Symptoms of Chronic Migraine in Children and Adolescents. 2015. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1427980899.

    MLA Style (8th edition)

  • Kroner, John. "Associated Symptoms of Chronic Migraine in Children and Adolescents." Master's thesis, University of Cincinnati, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1427980899

    Chicago Manual of Style (17th edition)

ucin1427980899
242
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This open access ETD is published by University of Cincinnati and OhioLINK.