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Computational Modeling of Laser Therapy of Port-Wine Stains- Based on Reduced Scattering Method

Ruchi, Sangeetika
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428070493

Abstract Details

2015, MS, University of Cincinnati, Engineering and Applied Science: Mechanical Engineering.
Laser treatment of Port-Wine Stains (PWS) was studied computationally by assuming a two dimensional skin model and using the reduced scattering method for the photon energy transport. The energy deposited during the laser irradiation of skin was based on a Gaussian laser profile. Alternating Direction Implicit finite difference method was used to investigate the effect of cryogenic spray cooling during laser irradiation on the skin temperature response. The computational model was developed in MATLAB and validated using experimental results available in the literature. Simulations were first run for the case of laser irradiation with a continuous spurt of cryogen which showed a drastic drop in the temperature rise as compared to the case without any cooling method. Then the effect of intermittent cryogen cooling accompanying laser irradiation was analyzed. To understand the outcome of preheating on the treatment procedure, preheating was computational modeled with continuous as well as intermittent cryogen cooling. It was found that by preheating the skin it is possible to raise the temperature of the blood vessels (responsible for PWS), by minimizing the danger of vessel necrosis. Preheating the skin increases the temperature of the entire skin model (layers of epidermis, dermis and blood) but since cryogen provides only selective cooling it protects the epidermis from any form of thermal injury, without affecting the temperature of blood vessels present in the dermis layer. It was also found that using cryogen spurt in intermittent intervals instead of a long continuous spurt further reduces the risk of vessel necrosis and other forms of thermal injury. Results showed that the maximum temperature rise is a weak function of the surface heat transfer coefficient however the temperature in the epidermis layer is strongly dependent on the surface heat transfer.
Milind Jog, Ph.D. (Committee Chair)
Shaaban Abdallah, Ph.D. (Committee Member)
Raj Manglik, Ph.D. (Committee Member)
86 p.
Mechanical Engineering
Port-Wine Stains; Cryogen Spray Cooling; Computational model; droplet impact; heat transfer

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Citations

  • Ruchi, S. (2015). Computational Modeling of Laser Therapy of Port-Wine Stains- Based on Reduced Scattering Method [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428070493

    APA Style (7th edition)

  • Ruchi, Sangeetika. Computational Modeling of Laser Therapy of Port-Wine Stains- Based on Reduced Scattering Method. 2015. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428070493.

    MLA Style (8th edition)

  • Ruchi, Sangeetika. "Computational Modeling of Laser Therapy of Port-Wine Stains- Based on Reduced Scattering Method." Master's thesis, University of Cincinnati, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1428070493

    Chicago Manual of Style (17th edition)

ucin1428070493
455
© 2015, some rights reserved.Creative Commons License Computational Modeling of Laser Therapy of Port-Wine Stains- Based on Reduced Scattering Method by Sangeetika Ruchi is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by University of Cincinnati and OhioLINK.