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Techniques for Finite Element Modeling and Remodeling of Bones with Applications to Pig Skulls

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2017, MS, University of Cincinnati, Engineering and Applied Science: Aerospace Engineering.
To better understand skull response after surgeries in patients born with an alveolar cleft, a finite element method (FEM) has been designed to predict how bone is strained during normal loading cycles of mastication. To test the effectiveness of treatment utilizing stem cells on resorbable scaffolds, a juvenile swine was operated by a surgically created alveolar cleft. Then, the FEM model of the pig skull was built based from pre- and post-surgery computed tomography (CT) to estimate strain dynamics in the healing bone. Scan resolutions were insufficient to visualize bone at the scale of trabeculae, a necessary item to determine how depositional fields in healing and growing bone will respond to loading. This is important because bone deposition is sensitive to both strain and material properties of depositional substrates. Hence, a detailed model is urgently needed with more accurate skull structure and mechanical properties. In this thesis, a new semi-automated method is proposed to build a more accurate skull model with microCT (µCT) scans. In addition to applying the new model in alveolar cleft repair, this new method can also be used to estimate remodeling algorithms incorporated with three dimensional (3D) finite element methods (FEM) script. In this way, finite element method (FEM) can been used to predict how mature bone partially remodels under mechanical loadings.
Gui-Rong Liu, Ph.D. (Committee Chair)
Yao Fu (Committee Member)
Donna Jones, Ph.D. (Committee Member)
69 p.

Recommended Citations

Citations

  • Zhu, Z. (2017). Techniques for Finite Element Modeling and Remodeling of Bones with Applications to Pig Skulls [Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1512045879980572

    APA Style (7th edition)

  • Zhu, Zimo. Techniques for Finite Element Modeling and Remodeling of Bones with Applications to Pig Skulls. 2017. University of Cincinnati, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1512045879980572.

    MLA Style (8th edition)

  • Zhu, Zimo. "Techniques for Finite Element Modeling and Remodeling of Bones with Applications to Pig Skulls." Master's thesis, University of Cincinnati, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1512045879980572

    Chicago Manual of Style (17th edition)