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30501.pdf (942.46 KB)
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Body Composition of Very Low Birth Weight Infants Fed Donor Breast Milk
Author Info
McNelis, Kera, M.D.
ORCID® Identifier
http://orcid.org/0000-0002-2592-8046
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535464232285332
Abstract Details
Year and Degree
2018, MS, University of Cincinnati, Medicine: Clinical and Translational Research.
Abstract
BACKGROUND: Donor breast milk is increasingly used as a supplemental feeding source for preterm infants when mother’s own milk supply is limited. Despite fortification, donor breast milk does not have the same nutritional content of a preterm infant’s own mother’s milk, and can be lacking in macronutrients needed for optimal growth. Air displacement plethysmography is validated for the measurement of neonatal body composition and can provide a snapshot of nutritional status that is predictive of later outcomes. OBJECTIVE: The goal of this study was to describe the body composition of very low birth weight infants fed donor breast milk and correlate the ratio of donor breast milk to maternal breast milk intake with lean and fat mass deposition. METHODS: Fat mass, lean mass, and body fat percentage were measured using air-displacement plethysmography. Nutritional intake details were recorded, and along with maternal characteristics, demographic data, and medical data, were used to develop a regression model that predicted body composition. RESULTS: Of the 67 enrolled infants, fat mass, lean mass, and body fat percentage were measured in 30 (45%) very low birth weight infants once they were stable on room air. Significant variables in the model for body fat percentage measured between 30+0 and 36+6 weeks corrected gestational age included sex, maternal age, and proportion of donor breast milk intake; together these explained 63% of variation in body fat percentage. Maternal height, maternal age, sex, and small for gestational age status were predictive of the variation in lean body mass, while proportion of donor breast milk intake was not a statistically significant characteristic in the lean body mass regression model. CONCLUSION: Donor breast milk intake is associated with less body fat deposition in very low birth weight infants.
Committee
Erin Haynes, Dr.P.H. (Committee Chair)
Brenda Poindexter (Committee Member)
Jun Ying, Ph.D. (Committee Member)
Pages
20 p.
Subject Headings
Nutrition
Keywords
body composition
;
neonatal
;
breast milk
;
nutrition
;
very low birth weight
;
preterm infants
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Citations
McNelis, M.D., K. (2018).
Body Composition of Very Low Birth Weight Infants Fed Donor Breast Milk
[Master's thesis, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535464232285332
APA Style (7th edition)
McNelis, M.D., Kera.
Body Composition of Very Low Birth Weight Infants Fed Donor Breast Milk.
2018. University of Cincinnati, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535464232285332.
MLA Style (8th edition)
McNelis, M.D., Kera. "Body Composition of Very Low Birth Weight Infants Fed Donor Breast Milk." Master's thesis, University of Cincinnati, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1535464232285332
Chicago Manual of Style (17th edition)
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Document number:
ucin1535464232285332
Download Count:
266
Copyright Info
© 2018, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.