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Full text of this paper is not available in the ETD Center. Copies may be available for inter-library loan from University of Cincinnati or may be available for purchase from Proquest/UMI

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THE NEUROPSYCHOLOGICAL CHARACTERIZATION OF CHILDREN OF PARENTS WITH BIPOLAR DISORDER

McDonough-Ryan, Patricia
http://rave.ohiolink.edu/etdc/view?acc_num=ucin990719045

Abstract Details

2001, PhD, University of Cincinnati, Arts and Sciences : Psychology.
The purpose of the present study was to investigate the pattern of neuropsychological strengths and weaknesses among children genetically at risk for bipolar disorder in an attempt to better understand early cognitive impairments associated with the illness. The neuropsychological functioning of children (ages 8-12) who had at least one biological parent with bipolar disorder (N=21) was compared to performance in a control group of children of healthy parents (N=20) matched for age, sex, socioeconomic status and race. The results indicate that at-risk children who met DSM-IV criteria for a mood disorder (N=11) as well as at-risk children who were not mood syndromal but had subsyndromal symptoms or were asymptomatic (N=10), performed more poorly on measures of executive functioning and were more likely to demonstrate a profile of a significant VIQ>PIQ discrepancy than control children. In addition, at-risk children with abnormal mood syndromes performed more poorly on measures of academic achievement than did non-syndromal at-risk children and healthy controls. These results extend the current literature on neuropsychological functioning of children at risk for bipolar disorder and suggest that both mood syndromal and non-syndromal children show specific cognitive impairments. The findings are consistent in part with the neuropsychological literature on adults with bipolar disorder and are most suggestive of primary executive dysfunction, rather than a right hemisphere impairment or nonverbal learning disability as previous literature has suggested. Executive impairments may be associated with the development and presentation of mood disorders in these children.
M. Ris (Advisor)
BIPOLAR DISORDER; CHILDREN AT RISK; NEUROPSYCHOLOGY OF BIPOLAR DISORDER

Recommended Citations

Citations

  • McDonough-Ryan, P. (2001). THE NEUROPSYCHOLOGICAL CHARACTERIZATION OF CHILDREN OF PARENTS WITH BIPOLAR DISORDER [Doctoral dissertation, University of Cincinnati]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ucin990719045

    APA Style (7th edition)

  • McDonough-Ryan, Patricia. THE NEUROPSYCHOLOGICAL CHARACTERIZATION OF CHILDREN OF PARENTS WITH BIPOLAR DISORDER. 2001. University of Cincinnati, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ucin990719045.

    MLA Style (8th edition)

  • McDonough-Ryan, Patricia. "THE NEUROPSYCHOLOGICAL CHARACTERIZATION OF CHILDREN OF PARENTS WITH BIPOLAR DISORDER." Doctoral dissertation, University of Cincinnati, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin990719045

    Chicago Manual of Style (17th edition)

ucin990719045
© 2001, all rights reserved.
This open access ETD is published by University of Cincinnati and OhioLINK.