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FABRICATION AND TESTING OF SCAFFOLDS FOR CELL GROWTH FROM IONIC LIQUID SOLUBILIZED FIBROIN

Gupta, Maneesh Kumar
http://rave.ohiolink.edu/etdc/view?acc_num=wright1197670563

Abstract Details

2007, Master of Science in Engineering (MSEgr), Wright State University, Biomedical Engineering.
The advent of tissue engineering has spurred research into developing materials to act as scaffolds for tissue growth. These scaffolds require materials capable of mimicking the in vivo conditions so that tissues can be grown effectively in vitro. Silk is an attractive biomaterial for use in tissue engineering applications because of its slow degradation, excellent mechanical properties, and biocompatibility. The major objective of the research in this thesis is to demonstrate a simple method to cast films directly from silk fibroin dissolved in an ionic liquid. The films cast from the silk ionic liquid solution were found to support normal keratinocyte proliferation and differentiation. The versatility of the silk ionic liquid solutions and the ability to process large amounts of silk into materials with controlled surface topography directly from the dissolved silk ionic liquid solution make it an interesting material for a wide variety of tissue engineering applications.
David Reynolds (Advisor)
64 p.
Tissue Engineering; Silk; Fibroin; Bombyx mori; Ionic liquid

Recommended Citations

Citations

  • Gupta, M. K. (2007). FABRICATION AND TESTING OF SCAFFOLDS FOR CELL GROWTH FROM IONIC LIQUID SOLUBILIZED FIBROIN [Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1197670563

    APA Style (7th edition)

  • Gupta, Maneesh. FABRICATION AND TESTING OF SCAFFOLDS FOR CELL GROWTH FROM IONIC LIQUID SOLUBILIZED FIBROIN. 2007. Wright State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=wright1197670563.

    MLA Style (8th edition)

  • Gupta, Maneesh. "FABRICATION AND TESTING OF SCAFFOLDS FOR CELL GROWTH FROM IONIC LIQUID SOLUBILIZED FIBROIN." Master's thesis, Wright State University, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=wright1197670563

    Chicago Manual of Style (17th edition)

wright1197670563
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© 2007, all rights reserved.
This open access ETD is published by Wright State University and OhioLINK.