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wright1221859953.pdf (2.81 MB)
ETD Abstract Container
Abstract Header
EVANESCENT MICROWAVE MICROSCOPY OF PORCINE SKIN TISSUE
Author Info
Kleismit, Richard A.
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=wright1221859953
Abstract Details
Year and Degree
2008, Master of Science (MS), Wright State University, Physics.
Abstract
This thesis describes the application of a custom designed λ/4 resonant coaxial probe to measurements of the complex permittivity of in vitro freshly excised porcine skin tissue. The dielectric properties of the organic material within the near field of the tip of the probe frustrates the electric field and measurably changes the resonant frequency and quality factor Q of the coaxial sensor, where the change in resonant frequency and quality factor of a tuned resonance is measured as a function of tip-sample separation. The design of the probe enables better spatial resolution than previously developed probes. The following studies were performed: (1) measurement of the complex permittivity of porcine tissue over a range of frequencies revealed values consistent with published literature; (2) the change in quality factor from the probe measurements was compared to a visual microscope analysis of histological slices from the same skin location, indicating that subsurface structures such as capillary beds, ducts of exocrine sweat glands, and vein lumen ducts can be detected; and (3) measurements of the dielectric properties of a puncture wound and several burn lesions of varying severity revealed easily detectable changes, indicating that the probe has potential for evaluating and monitoring skin conditions. In addition, a new quantitative two point relationship between the real and imaginary parts of the materials complex permittivity related to the resonant frequency and quality factor shift using the method of images is developed, presented, and used in the above described skin studies. The two-point model describing the probe tip-sample interaction is capable of producing quantitative complex permittivity values for organic and biological materials.
Committee
Brent Foy, PhD (Advisor)
Gregory Kozlowski, PhD (Committee Member)
Paul Hanny, PhD (Committee Member)
Pages
83 p.
Subject Headings
Physics
Keywords
evanescent
;
sensor
;
microwave
;
biomaterial characterization
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Citations
Kleismit, R. A. (2008).
EVANESCENT MICROWAVE MICROSCOPY OF PORCINE SKIN TISSUE
[Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1221859953
APA Style (7th edition)
Kleismit, Richard.
EVANESCENT MICROWAVE MICROSCOPY OF PORCINE SKIN TISSUE.
2008. Wright State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=wright1221859953.
MLA Style (8th edition)
Kleismit, Richard. "EVANESCENT MICROWAVE MICROSCOPY OF PORCINE SKIN TISSUE." Master's thesis, Wright State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=wright1221859953
Chicago Manual of Style (17th edition)
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Document number:
wright1221859953
Download Count:
866
Copyright Info
© 2008, all rights reserved.
This open access ETD is published by Wright State University and OhioLINK.