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wright1302798053.pdf (17.97 MB)
ETD Abstract Container
Abstract Header
Strategies for long-term renal allograft survival in IgA nephropathy patients
Author Info
Lintz, Erin E.
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=wright1302798053
Abstract Details
Year and Degree
2011, Master of Science (MS), Wright State University, Microbiology and Immunology.
Abstract
IgA nephropathy is one of the most common kidney diseases worldwide. Most IgA nephropathy patients will undergo a kidney transplant as a treatment. Treatment currently includes the use of immunosuppressants which are necessary to prevent graft rejection but present harmful side-effects when taken long-term. This review focuses on strategies which have the ability to promote tolerance of both donor and recipient cells within a transplant recipient. Such strategies allow development of mixed chimerism and thereby alleviate the need for long-term immunosuppressant usage in allograft recipients. These strategies could be applied to IgA nephropathy patients to allow kidney allograft acceptance without the use of long-term immunosuppressant usage. These strategies may prevent recurrence of IgA nephropathy in kidney grafts.
Committee
Nancy Bigley, PhD (Committee Chair)
Barbara Hull, PhD (Committee Member)
Julian Cambronero, PhD (Committee Member)
Andrew Hsu, PhD (Other)
Pages
62 p.
Subject Headings
Immunology
;
Microbiology
Keywords
IgA nephropathy
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Citations
Lintz, E. E. (2011).
Strategies for long-term renal allograft survival in IgA nephropathy patients
[Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1302798053
APA Style (7th edition)
Lintz, Erin.
Strategies for long-term renal allograft survival in IgA nephropathy patients.
2011. Wright State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=wright1302798053.
MLA Style (8th edition)
Lintz, Erin. "Strategies for long-term renal allograft survival in IgA nephropathy patients." Master's thesis, Wright State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1302798053
Chicago Manual of Style (17th edition)
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Document number:
wright1302798053
Download Count:
308
Copyright Info
© 2011, all rights reserved.
This open access ETD is published by Wright State University and OhioLINK.