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WSUThesis_Giacherio.pdf (39.98 MB)
ETD Abstract Container
Abstract Header
Evaluation of Functional Near Infrared Spectroscopy (fNIRS) for Assessment of the Visual and Motor Cortices in Adults
Author Info
Giacherio, Brenna
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=wright1401816241
Abstract Details
Year and Degree
2014, Master of Science in Engineering (MSEgr), Wright State University, Biomedical Engineering.
Abstract
Introduction: Functional near-infrared spectroscopy (fNIRS) is a relatively young technique in the field of medical imaging. As such, it has yet to be widely implemented for clinical use, despite its promising advantages. However, unlike fMRI-its much bulkier and costly counterpart-fNIRS has yet to be proven as a standalone imaging tool within a clinical setting, particularly that of ophthalmology or physical therapy. Methods: Ten healthy young adults (23.8 ± 4.8 years) participated in the study. Activation of the visual cortex was achieved utilizing various reversing checkerboard stimuli across three data collection sessions for each participant. Further, activation of the motor cortex was achieved using simple grasping and finger tapping tasks. Data was processed with MATLAB scripts and statistical analysis was performed using JMP. Results: Quantitatively, statistically significant differences in the level of activation were elicited by some stimuli, but not others. No differences were discovered between the levels of activation for the two motor tasks. However, as expected, differences were observed between the hair types of participants for both visual and motor activation. Additionally, one of the three data collection sessions for each participant tended to give statistically different results than the other two. Qualitatively, the number of stimulus events and data channels which showed activation were inconsistent. Conclusions: It has been shown, both previously (by others) and within this study, that fNIRS is indeed feasible for investigating the visual and motor cortices. However, a reliable level of robustness and sensitivity is required for clinical implementation. This research shows that fNIRS can in fact achieve an appropriate level of sensitivity for visual studies, but it still lacks an appropriate level of robustness in terms of repeatability and corporal differences for assessment of visual or motor dysfunction.
Committee
Nasser Kashou, Ph.D. (Advisor)
Frank Ciarallo, Ph.D. (Committee Member)
Thomas Hangartner, Ph.D., FAAPM (Committee Member)
Ping He, Ph.D. (Committee Member)
Pages
150 p.
Subject Headings
Biomedical Engineering
;
Biomedical Research
Keywords
fNIRS
;
NIRS
;
visual cortex
;
motor cortex
;
finger tapping
;
checkerboard stimulus
;
clinical use
;
near infrared spectroscopy
;
ophthalmology
;
physical therapy
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Citations
Giacherio, B. (2014).
Evaluation of Functional Near Infrared Spectroscopy (fNIRS) for Assessment of the Visual and Motor Cortices in Adults
[Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1401816241
APA Style (7th edition)
Giacherio, Brenna.
Evaluation of Functional Near Infrared Spectroscopy (fNIRS) for Assessment of the Visual and Motor Cortices in Adults.
2014. Wright State University, Master's thesis.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=wright1401816241.
MLA Style (8th edition)
Giacherio, Brenna. "Evaluation of Functional Near Infrared Spectroscopy (fNIRS) for Assessment of the Visual and Motor Cortices in Adults." Master's thesis, Wright State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=wright1401816241
Chicago Manual of Style (17th edition)
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Document number:
wright1401816241
Download Count:
400
Copyright Info
© 2014, all rights reserved.
This open access ETD is published by Wright State University and OhioLINK.