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Terahertz Spectroscopic Breath Analysis as a Viable Analytical Chemical Sensing Technique

Schueler, Robert M.
http://orcid.org/0000-0001-7725-4736
http://rave.ohiolink.edu/etdc/view?acc_num=wright1464170300

Abstract Details

2016, Master of Science (MS), Wright State University, Physics.
The ability to quantify trace chemicals in human breath enables the possibility of identifying breath biomarkers to aid in diagnosis. The vast majority of the studies in the analytical breath analysis rely on GC-MS techniques for quantification of the human breath composition1,2,3,4. THz spectroscopy of breath is rapid, sensitive, and highly specific molecular identification in complex mixtures containing 10-100 analytes with near `absolute' specificity. THz spectroscopic breath analyzers require chemical preconcentration. A newly developed custom preconcentrator was constructed and compared in its performance to a commercial system. Unlike the commercial counterpart, the new system does not require cryogenic liquids, is compact, and offers significant advantages in terms of ease of operation and facilitates further development of THz breath sensors. Its preconcentration efficiency was assessed. The THz spectrometer coupled with the custom preconcentrator demonstrated first THz detection of breath isoprene, a chemical not detected with the commercial device.
Ivan Medvedev , Ph.D. (Advisor)
Doug Petkie, Ph.D. (Committee Member)
Brent Foy, Ph.D. (Committee Member)
53 p.
Physics
spectroscopy , TERAHERTZ , Breath,THz, preconcentrator

Recommended Citations

Citations

  • Schueler, R. M. (2016). Terahertz Spectroscopic Breath Analysis as a Viable Analytical Chemical Sensing Technique [Master's thesis, Wright State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=wright1464170300

    APA Style (7th edition)

  • Schueler, Robert. Terahertz Spectroscopic Breath Analysis as a Viable Analytical Chemical Sensing Technique. 2016. Wright State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=wright1464170300.

    MLA Style (8th edition)

  • Schueler, Robert. "Terahertz Spectroscopic Breath Analysis as a Viable Analytical Chemical Sensing Technique." Master's thesis, Wright State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1464170300

    Chicago Manual of Style (17th edition)

wright1464170300
770
© 2016, some rights reserved.Creative Commons License Terahertz Spectroscopic Breath Analysis as a Viable Analytical Chemical Sensing Technique by Robert M. Schueler is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by Wright State University and OhioLINK.