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Studies Toward the Synthesis of Aminosugars Related to Components of the S. aureus Capsular Polysaccharide

Fluxe, Andrew James
http://rave.ohiolink.edu/etdc/view?acc_num=ysu1008343078

Abstract Details

2001, Master of Science in Chemistry, Youngstown State University, Department of Chemistry.
The following work describes new synthetic pathways toward one of the monosaccharide units, and analogs thereof, of the Staphylococcus aureus Type 5 and Type 8 capsular polysaccharides. Two main approaches to N-acetyl-D-mannosamine uronic acid were investigated. The first method utilized dithioacetal chemistry in which a pentose sugar was extended by one carbon atom via a nucleophilic addition to afford a hexose sugar derivative. The second synthetic procedure involved the addition of various nucleophiles to a selective protected D-mannosamine derivative to afford progenitors of D-ManAcA analogs.
Peter Norris (Advisor)
83 p.
Chemistry, General
Monosaccharides; Poloysaccharides; Staphylococcus aureus

Recommended Citations

Citations

  • Fluxe, A. J. (2001). Studies Toward the Synthesis of Aminosugars Related to Components of the S. aureus Capsular Polysaccharide [Master's thesis, Youngstown State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1008343078

    APA Style (7th edition)

  • Fluxe, Andrew. Studies Toward the Synthesis of Aminosugars Related to Components of the S. aureus Capsular Polysaccharide. 2001. Youngstown State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ysu1008343078.

    MLA Style (8th edition)

  • Fluxe, Andrew. "Studies Toward the Synthesis of Aminosugars Related to Components of the S. aureus Capsular Polysaccharide." Master's thesis, Youngstown State University, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1008343078

    Chicago Manual of Style (17th edition)

ysu1008343078
799
© 2001, all rights reserved.
This open access ETD is published by Youngstown State University and OhioLINK.