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Synthons of UDP-N-acetyl-L-Fucosamine (UDP-L-FucNAc) as potential inhibitors of Staphylococcus aureus Capsular Polysaccharide Biosynthesis

Ngoje, Philemon O.

Abstract Details

2015, Master of Science in Chemistry, Youngstown State University, Department of Chemistry.
Non-traceless modified Staudinger reaction was utilized as a safe method in this work to synthesize novel synthons of UDP-N-acetyl-L-fucosamine as potential inhibitors of or substrates for bacterial glycosyltransfares, responsible for the biosynthesis of the capsular polysaccharide of Staphyloccous aureus. Carbon-13 and proton spectral techniques were used in the characterization of formed products.
Peter Norris, PhD (Advisor)
John Jackson, PhD (Committee Member)
Nina Stourman, PhD (Committee Member)
104 p.

Recommended Citations

Citations

  • Ngoje, P. O. (2015). Synthons of UDP-N-acetyl-L-Fucosamine (UDP-L-FucNAc) as potential inhibitors of Staphylococcus aureus Capsular Polysaccharide Biosynthesis [Master's thesis, Youngstown State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1441880943

    APA Style (7th edition)

  • Ngoje, Philemon. Synthons of UDP-N-acetyl-L-Fucosamine (UDP-L-FucNAc) as potential inhibitors of Staphylococcus aureus Capsular Polysaccharide Biosynthesis . 2015. Youngstown State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ysu1441880943.

    MLA Style (8th edition)

  • Ngoje, Philemon. "Synthons of UDP-N-acetyl-L-Fucosamine (UDP-L-FucNAc) as potential inhibitors of Staphylococcus aureus Capsular Polysaccharide Biosynthesis ." Master's thesis, Youngstown State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1441880943

    Chicago Manual of Style (17th edition)