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Investigating Mediators of Change in Prolonged Exposure Therapy and Sertraline for Chronic PTSD

Baier, Allison L.
http://orcid.org/0000-0003-1077-8257
http://rave.ohiolink.edu/etdc/view?acc_num=case1528480809790197

Abstract Details

2018, Master of Arts, Case Western Reserve University, Psychology.
While efficacious psychological treatments for PTSD exist, little is known about the mechanisms by which treatment leads to symptom reduction. A better understanding of these processes is imperative for personalizing treatment and augmenting clinical outcomes. The current study examined three putative mediators—between session habituation, negative trauma-related belief change, and the therapeutic alliance—with one another and with PTSD symptom change in 144 individuals receiving prolonged exposure (PE) or sertraline for PTSD. Using time-lagged mixed regression models that disaggregated within- and between-patient effects, three significant findings emerged: improvements in alliance predicted next session PTSD symptom reduction in both treatments, improvements in alliance predicted next session belief change in PE, and belief change predicted next session alliance improvements in both treatments. Notably, habituation was not a significant predictor of next session PTSD symptom change or alliance. Findings are discussed in the context of clinical implications and methodological implications for mechanism research.
Norah Feeny, Ph.D. (Committee Chair)
Julie Exline, Ph.D. (Committee Member)
Arin Connell, Ph.D. (Committee Member)
92 p.
Clinical Psychology
PTSD, mediators, habituation, cognitive beliefs, alliance, PE, sertraline

Recommended Citations

Citations

  • Baier, A. L. (2018). Investigating Mediators of Change in Prolonged Exposure Therapy and Sertraline for Chronic PTSD [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1528480809790197

    APA Style (7th edition)

  • Baier, Allison. Investigating Mediators of Change in Prolonged Exposure Therapy and Sertraline for Chronic PTSD . 2018. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1528480809790197.

    MLA Style (8th edition)

  • Baier, Allison. "Investigating Mediators of Change in Prolonged Exposure Therapy and Sertraline for Chronic PTSD ." Master's thesis, Case Western Reserve University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1528480809790197

    Chicago Manual of Style (17th edition)

case1528480809790197
318
© 2018, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.
Release 3.2.12