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Analyzing the Cytocompatibility of Polymeric Biomaterials Synthesized Using Ring-Opening Copolymerization

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2023, Master of Science (MS), Ohio University, Biomedical Engineering (Engineering and Technology).
Polymeric materials form a major pillar and cornerstone in the manufacturing of devices for medical uses. Traditional synthesis and manufacturing of these materials have utilized metal-catalyzed reactions which run the risk of leaving trace amounts of metal ions in the final synthesis products. Because of the known detriments of metal exposure to the body, a new direction of research has been to explore the use of organic catalysts in polymer synthesis. In this thesis, the safety of the organocatalytic system is explored through a determination of the cytotoxic potential of these materials as well as their effects on cell proliferative behavior. The cellular impacts of the catalysts and synthesis materials are shown to be safe at reasonably achievable biological concentrations and warrant further exploration for use in implantable biomedical devices.
Andrew Weems, PhD (Advisor)
103 p.

Recommended Citations

Citations

  • Casa, C. (2023). Analyzing the Cytocompatibility of Polymeric Biomaterials Synthesized Using Ring-Opening Copolymerization [Master's thesis, Ohio University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1687961053538804

    APA Style (7th edition)

  • Casa, Charles. Analyzing the Cytocompatibility of Polymeric Biomaterials Synthesized Using Ring-Opening Copolymerization. 2023. Ohio University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1687961053538804.

    MLA Style (8th edition)

  • Casa, Charles. "Analyzing the Cytocompatibility of Polymeric Biomaterials Synthesized Using Ring-Opening Copolymerization." Master's thesis, Ohio University, 2023. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1687961053538804

    Chicago Manual of Style (17th edition)