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Anesthetic Efficacy Of 4% Prilocaine Plus 2% Lidocaine With 1:100,000 Epinephrine For Inferior Alveolar Nerve Blocks

Cook, Olivia B, DMD

Abstract Details

2017, Master of Science, Ohio State University, Dentistry.
Introduction: Some clinicians combine plain anesthetics with those containing epinephrine to increase pulpal anesthetic success and decrease the pain of injection. The purpose of this study was to evaluate the combination of prilocaine and lidocaine when used for inferior alveolar nerve blocks in subjects with vital, asymptomatic teeth. Materials and Methods: One hundred eighteen subjects were given 1.8 mL 4% prilocaine plus 1.8 mL 2% lidocaine with 1:100,000 epinephrine or two injections of 1.8 mL 2% lidocaine with 1:100,000 epinephrine for the inferior alveolar nerve block at two separate appointments. Subjects rated the pain of needle insertion, needle placement and solution deposition on a Heft-Parker VAS. The first and second molars, first and second premolars and incisors were tested with an EPT every 4 minutes for 57 minutes for pulpal anesthesia. Anesthesia was considered successful when two consecutive 80 readings were obtained within 17 minutes post-injection and the 80 reading was continuously sustained for one hour. Results: Both groups reported needle insertion and solution deposition pain in the mild range with the prilocaine group being significantly less painful. Mean pain for both groups for needle placement was moderate with the prilocaine group having significantly lower pain ratings. Anesthetic success was not significantly different between the groups. Summary and Conclusions: The combination of 4% prilocaine and 2% lidocaine with 1:100,000 epinephrine produced less injection pain. Anesthetic success did not improve with the prilocaine/lidocaine combination.
John Nusstein, DDS, MS (Advisor)
Al Reader, DDS, MS (Committee Member)
Melissa Drum, DDS, MS (Committee Member)
Sara Fowler, DMD, MS (Committee Member)
John Draper, PhD (Committee Member)
102 p.

Recommended Citations

Citations

  • Cook, DMD, O. B. (2017). Anesthetic Efficacy Of 4% Prilocaine Plus 2% Lidocaine With 1:100,000 Epinephrine For Inferior Alveolar Nerve Blocks [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu149945067803552

    APA Style (7th edition)

  • Cook, DMD, Olivia. Anesthetic Efficacy Of 4% Prilocaine Plus 2% Lidocaine With 1:100,000 Epinephrine For Inferior Alveolar Nerve Blocks. 2017. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu149945067803552.

    MLA Style (8th edition)

  • Cook, DMD, Olivia. "Anesthetic Efficacy Of 4% Prilocaine Plus 2% Lidocaine With 1:100,000 Epinephrine For Inferior Alveolar Nerve Blocks." Master's thesis, Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu149945067803552

    Chicago Manual of Style (17th edition)