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A Review of the Higher-Order Structures and Applications of Collagen Mimetic Peptides

Goldmeier, Max

Abstract Details

2016, Master of Science, University of Akron, Polymer Science.
Collagen is a protein that is a major component of the human body and makes up thirty percent of the total protein in the human body. Collagen mimetic peptides (CMPs) have been used to study the formation of the triple helix of collagen and its higher-ordered structures. This article discusses how CMPs have been used to learn about the physical properties of the triple helix and how the amino acid sequence affects the physical properties, formation, and stability of the triple helix. CMPs have also been designed to form higher-ordered structures for various applications. This work reviews the design principles and strategies employed with various interactions to form higher-ordered structures from CMPs. These strategies include the use of electrostatic interactions, the incorporation of cysteine knots, and metal-induced self-assembly, among others. Many of these higher-ordered structures have applications such as biomolecule attraction, cellular adhesion, nanowire fabrication, and hydrogel formation.
Nita Sahai, PhD (Advisor)
93 p.

Recommended Citations

Citations

  • Goldmeier, M. (2016). A Review of the Higher-Order Structures and Applications of Collagen Mimetic Peptides [Master's thesis, University of Akron]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=akron1468872481

    APA Style (7th edition)

  • Goldmeier, Max. A Review of the Higher-Order Structures and Applications of Collagen Mimetic Peptides. 2016. University of Akron, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=akron1468872481.

    MLA Style (8th edition)

  • Goldmeier, Max. "A Review of the Higher-Order Structures and Applications of Collagen Mimetic Peptides." Master's thesis, University of Akron, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=akron1468872481

    Chicago Manual of Style (17th edition)