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A SURFACE-BASED DEFORMABLE IMAGE REGISTRATION WITH APPLICATION TO BREAST CANCER RADIATION THERAPY

Theeranaew, Wanchat

Abstract Details

2008, Master of Engineering, Case Western Reserve University, Systems and Control Engineering.
In this paper, a new form of surface-based deformable image registration is developed for use in image-guided radiation therapy (IGRT) of breast cancer patients. A special laser scanner is used to obtain inter-fraction 3D images of the target volume, with 3-4 fixed landmarks located at the rigid base of the breast. By comparing the image-ofthe-day with the initial-fraction image, a rigid-body registration is first performed on the landmarks to correct the patient set-up position. This is then followed by a surface comparison scheme to estimate the extent of deformity of the target volume. In this paper, deformity is represented by the distance between the two surfaces. With the surface images stored as triangular meshes, deformity is determined as the collection of distances from the centers of triangular meshes of a surface to their respective closest triangular pieces of another surface. A ray-to-triangle intersection algorithm is used in the distance calculation, and a neighborhood-search technique is devised to substantially increase the calculation speed while maintaining the accuracy. Experimental measurements using phantoms were used to test the accuracy and speed of the overall image registration scheme. Preliminary results indicate that the proposed system is fast and accurate suitable for further adaptation for clinical application.
Vira Chankong (Advisor)
74 p.

Recommended Citations

Citations

  • Theeranaew, W. (2008). A SURFACE-BASED DEFORMABLE IMAGE REGISTRATION WITH APPLICATION TO BREAST CANCER RADIATION THERAPY [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1200427318

    APA Style (7th edition)

  • Theeranaew, Wanchat. A SURFACE-BASED DEFORMABLE IMAGE REGISTRATION WITH APPLICATION TO BREAST CANCER RADIATION THERAPY. 2008. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1200427318.

    MLA Style (8th edition)

  • Theeranaew, Wanchat. "A SURFACE-BASED DEFORMABLE IMAGE REGISTRATION WITH APPLICATION TO BREAST CANCER RADIATION THERAPY." Master's thesis, Case Western Reserve University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=case1200427318

    Chicago Manual of Style (17th edition)