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ANTIBIOTIC DELIVERY SYSTEM FOR SURGICAL SITE INFECTION PREVENTION IN SPINAL IMPLANT SURGERY

Mandavyapuram, Hima Bindu
http://rave.ohiolink.edu/etdc/view?acc_num=case1275624787

Abstract Details

2010, Master of Sciences, Case Western Reserve University, Biology.
A surgical site infection (SSI) is an infection that occur post surgery at the site of surgical incision. Around 1.5 million SSI infections are reported in the United States each year. These surgical site infections remain a major cause of post-operative illness,morbidity and less frequent cause of death in the surgical patient. Therefore, there is a considerable demand for improvement in the existing therapeutic outcomes for prevention of surgical site infection. The objective of this proposal is to study the functional ability of the Arteriocyte’s Magellan® derived autologous platelet rich plasma (PRP) coupled with an antibiotic, Kefzol (cefazolin. sodium salt) to prevent the incidence of surgical site infection in post-operative spinal surgery. The underlying hypothesis of this proposal is the use of autologous platelet rich plasma gel as a continuous antibiotic delivery vehicle for prevention of surgical site infection in patients undergoing lumbar spinal fusion.
Christopher Cullis, PhD (Advisor)
Ramasamy Sakthivel, PhD (Committee Member)
Jolly Emmitt, PhD (Committee Member)
Mark Willis, PhD (Committee Chair)
Biology
Magellan; Arteriocyte; cefazolin; Platelet; SURGICAL; INFECTION; PRP

Recommended Citations

Citations

  • Mandavyapuram, H. B. (2010). ANTIBIOTIC DELIVERY SYSTEM FOR SURGICAL SITE INFECTION PREVENTION IN SPINAL IMPLANT SURGERY [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1275624787

    APA Style (7th edition)

  • Mandavyapuram, Hima Bindu. ANTIBIOTIC DELIVERY SYSTEM FOR SURGICAL SITE INFECTION PREVENTION IN SPINAL IMPLANT SURGERY. 2010. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1275624787.

    MLA Style (8th edition)

  • Mandavyapuram, Hima Bindu. "ANTIBIOTIC DELIVERY SYSTEM FOR SURGICAL SITE INFECTION PREVENTION IN SPINAL IMPLANT SURGERY." Master's thesis, Case Western Reserve University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1275624787

    Chicago Manual of Style (17th edition)

case1275624787
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© 2010, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.