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Characteristics and usefulness of interfascicular contacts in peripheral nerve recording

Kolb, Ilya
http://rave.ohiolink.edu/etdc/view?acc_num=case1347309212

Abstract Details

2013, Master of Sciences (Engineering), Case Western Reserve University, Biomedical Engineering.
Neural interfaces have been used in conjunction with source separation algorithms to address the challenge of extracting useful command signals from nerves. A peripheral nerve interface is generally useful for signal extraction if it (1) exhibits favorable recording characteristics such as signal-to-noise ratio and (2) provides as many independent channels of neural information as possible. We investigated the usefulness of novel interfascicular electrodes in acute experiments on the rabbit sciatic nerve (n = 4). Directed interfascicular contacts were found to record compound action potentials (CAPs) with a mean SNR (at p = 0.05) of 24.5 dB with respect to interference sources. Contacts that (1) faced opposite directions and (2) were placed in various positions within the epineurium were found to record independent information from the nerve (mixing matrix |det(H)|>0.05 for all electrode configurations). This neural information recorded using interfascicular electrodes may potentially be useful for command signal extraction algorithms.
Dustin Tyler, PhD (Advisor)
Dominique Durand, PhD (Committee Member)
Christian Zorman, PhD (Committee Member)
65 p.
Biomedical Engineering; Neurology; Neurosciences
interfascicular; peripheral nerve; neural recording; source separation

Recommended Citations

Citations

  • Kolb, I. (2013). Characteristics and usefulness of interfascicular contacts in peripheral nerve recording [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1347309212

    APA Style (7th edition)

  • Kolb, Ilya. Characteristics and usefulness of interfascicular contacts in peripheral nerve recording. 2013. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1347309212.

    MLA Style (8th edition)

  • Kolb, Ilya. "Characteristics and usefulness of interfascicular contacts in peripheral nerve recording." Master's thesis, Case Western Reserve University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1347309212

    Chicago Manual of Style (17th edition)

case1347309212
490
© 2012, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.