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Instrumentation and Control System to Quantify Colonic Activity

Abstract Details

2016, Master of Sciences (Engineering), Case Western Reserve University, Biomedical Engineering.
Neurogenic bowel dysfunction (NBD) is a common and socially debilitating issue for people with spinal cord injury. Our lab aims to develop a new treatment approach for NBD using electrical stimulation. In order to conduct this research, we have developed instrumentation to record colon pressure and diameter in sufficient spatial resolution to quantify colon storage and excretion. We have also developed a control system to record from our instrumentation, generate electrical stimulation patterns and allow for user control during experimentation. Both the instrumentation and control system have been validated on the bench and in-vivo for real-time quantification of colonic activity. Our setup has been used to conduct feline experiments and will act as a platform for future human studies.
Kenneth Gustafson (Advisor)
Dennis Bourbeau (Committee Member)
Dustin Tyler (Committee Member)
Abidemi Ajiboye (Committee Member)
156 p.

Recommended Citations

Citations

  • Aamoth, K. (2016). Instrumentation and Control System to Quantify Colonic Activity [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1459190138

    APA Style (7th edition)

  • Aamoth, Kelsey. Instrumentation and Control System to Quantify Colonic Activity. 2016. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1459190138.

    MLA Style (8th edition)

  • Aamoth, Kelsey. "Instrumentation and Control System to Quantify Colonic Activity." Master's thesis, Case Western Reserve University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1459190138

    Chicago Manual of Style (17th edition)