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Characterizing the Association Between Mandible Mechanical Properties and Function in the Rabbit

White, Brandon M
http://rave.ohiolink.edu/etdc/view?acc_num=case1506426954676547

Abstract Details

2018, Master of Sciences (Engineering), Case Western Reserve University, Biomedical Engineering.
Bony defects, especially those in load-bearing bones, represent a significant clinical problem with current therapeutic options that leave much to be desired. The next generation of synthetic bone graft materials should seek to provide the immediate return of functional ability in addition to enhancing long-term healing. The former can be accomplished by providing the defect with the mechanical support necessary to perform under normal physiological conditions. Currently, there is no method to associate mechanical properties of a bone to its useful function (i.e. chewing, walking, etc.). This study seeks to address this gap by developing an animal model in the rabbit that uses their teeth as a functional assay correlated to the whole bone mechanical properties of the mandible using ex-vivo four-point bending. The results of this study suggest that further development of our rabbit model is merited.
Steven Eppell, PhD (Advisor)
Jonathan Baskin, MD (Committee Member)
Ozan Akkus, PhD (Committee Member)
Biomedical Engineering
Biomechanics; Bone substitute material; critical size defect

Recommended Citations

Citations

  • White, B. M. (2018). Characterizing the Association Between Mandible Mechanical Properties and Function in the Rabbit [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1506426954676547

    APA Style (7th edition)

  • White, Brandon. Characterizing the Association Between Mandible Mechanical Properties and Function in the Rabbit. 2018. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1506426954676547.

    MLA Style (8th edition)

  • White, Brandon. "Characterizing the Association Between Mandible Mechanical Properties and Function in the Rabbit." Master's thesis, Case Western Reserve University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1506426954676547

    Chicago Manual of Style (17th edition)

case1506426954676547
463
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This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.