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FLEXIBLE, SKIN COUPLED MICROPHONE ARRAY FOR POINT OF CARE VASCULAR ACCESS MONITORING

Panda, Binit
http://rave.ohiolink.edu/etdc/view?acc_num=case1560348601743654

Abstract Details

2019, Master of Sciences, Case Western Reserve University, Biomedical Engineering.
The main goal of this thesis is to develop a flexible and body-conformal sensor for vascular access stenosis characterization. Vascular accesses are monitored through physical examination by medical personnel. These examinations are time consuming and subjective, thus creating a challenge for long term monitoring and an opportunity for automated analysis. In our method, we record phonoangiograms from vascular access phantoms through a custom-made flexible array of piezoelectric sensors. These signals are processed through an autoregressive bruit- enhancing filter which used a nonlinear, sub-band frequency-domain linear prediction approach to amplify the systolic pulses of the blood flow and associated stenosis related turbulence while attenuating inter-pulse intervals and artifacts due to ambient noise. Features like auditory spectral centroid (ASC) and auditory spectral flux (ASF) are extracted from the wavelet coefficients which are computed over 6 octaves with 12 voices/octave, starting at scale 3. Finally, we show that this piezoelectric sensor in combination with signal processing techniques can i) localize stenosis within 1 cm of the actual location, and ii) differentiate the degree of stenosis into three grades (mild, moderate and severe) in vitro. These results were confirmed with statistical analysis and the performance of the extracted features was also tested with a threshold-based stenosis detection classifier to mimic a clinical screening scenario aimed at identifying at-risk patients.
Soumyajit Mandal, PhD (Committee Chair)
Dominique Durand, PhD (Committee Member)
Colin Drummond, PhD (Committee Member)
Steve Majerus, PhD (Committee Member)
70 p.
Biomedical Engineering; Biomedical Research
Phonoangiogram, wavelet, flex sensor, blood sound, bruit, Auditory spectral centroid, flux, Phantom

Recommended Citations

Citations

  • Panda, B. (2019). FLEXIBLE, SKIN COUPLED MICROPHONE ARRAY FOR POINT OF CARE VASCULAR ACCESS MONITORING [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1560348601743654

    APA Style (7th edition)

  • Panda, Binit . FLEXIBLE, SKIN COUPLED MICROPHONE ARRAY FOR POINT OF CARE VASCULAR ACCESS MONITORING. 2019. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1560348601743654.

    MLA Style (8th edition)

  • Panda, Binit . "FLEXIBLE, SKIN COUPLED MICROPHONE ARRAY FOR POINT OF CARE VASCULAR ACCESS MONITORING." Master's thesis, Case Western Reserve University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1560348601743654

    Chicago Manual of Style (17th edition)

case1560348601743654
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© 2019, some rights reserved.Creative Commons License FLEXIBLE, SKIN COUPLED MICROPHONE ARRAY FOR POINT OF CARE VASCULAR ACCESS MONITORING by Binit Panda is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Based on a work at etd.ohiolink.edu.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.