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Thesis_EloiseMiller.pdf (6.45 MB)

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Building a synthetic periodontal ligament: collagen nanostructures on titanium

Miller, Eloise Peyton
http://rave.ohiolink.edu/etdc/view?acc_num=case1586422711694101

Abstract Details

2020, Master of Sciences (Engineering), Case Western Reserve University, Biomedical Engineering.
Clinical complications revolving around dental implants present significant clinical problems. Many of these complications, such as infection and aesthetic issues, could be remedied by the addition of an artificial biomimetic periodontal ligament at the interface of the titanium implant and the alveolar bone. This study seeks to mimic the natural structure of the periodontal ligament found around natural teeth roots by conjugating collagen fibrils perpendicularly to a titanium surface. The results of this study show proof-of-concept that collagen molecules can be bound end-on to a titanium surface, laying the groundwork for the development of artificial periodontal ligament. Further development of the ligament-building protocol is necessary to produce a bio-functional tissue.
Steven Eppell (Committee Chair)
Anirban Sen Gupta (Committee Member)
Leena Palomo (Committee Member)
Jonathan Pokorski (Committee Member)
192 p.
Biomedical Engineering

Recommended Citations

Citations

  • Miller, E. P. (2020). Building a synthetic periodontal ligament: collagen nanostructures on titanium [Master's thesis, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=case1586422711694101

    APA Style (7th edition)

  • Miller, Eloise. Building a synthetic periodontal ligament: collagen nanostructures on titanium. 2020. Case Western Reserve University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=case1586422711694101.

    MLA Style (8th edition)

  • Miller, Eloise. "Building a synthetic periodontal ligament: collagen nanostructures on titanium." Master's thesis, Case Western Reserve University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1586422711694101

    Chicago Manual of Style (17th edition)

case1586422711694101
469
© 2020, all rights reserved.
This open access ETD is published by Case Western Reserve University School of Graduate Studies and OhioLINK.