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Distress and Quality of Life in Bone Marrow Transplant Patients

Bautista, Maria Elizabeth

Abstract Details

2016, Doctor of Nursing Practice , Case Western Reserve University, School of Nursing.
The importance of distress screening has been acknowledged nationally and is the recognized standard of care in oncology patients. Patients who undergo bone marrow transplant (BMT) are known to suffer from distress, which can be psychological, physical, social and/or spiritual in nature. Approximately 40-55% of BMT patients are distressed pre-transplant, a higher rate than the general oncology population. BMT healthcare providers need to be aware of the psychosocial struggles that patients experience prior to transplant and throughout their cancer trajectory. The overall aim of this scholarly project was to determine if distress screening at pre-transplantation was associated with a predicted overall QOL of BMT patients post-transplantation. Additional research questions aimed to determine the most prevalent distressing problems in this population in order to target key nursing interventions. The conceptual framework is based on the Model of QOL adapted for BMT. Key variables include distress and QOL in BMT patients. According to the National Comprehensive Cancer Network, distress is defined as “a multifactorial unpleasant emotional experience of a psychological (cognitive, behavioral, emotional), social, &/or spiritual nature that may interfere with the ability to cope effectively with cancer, its physical symptoms and its treatment”. QOL, according to Grant & Ferrell, is defined as “as a personal statement of positivity or negativity of attributes (psychological well being, physical well-being, sequel of disease and treatment, social and interpersonal well-being and financial and material well-being) that characterize one’s life.” A descriptive, retrospective design was used. A convenience sample of fifty-six new allogeneic and autologous BMT patients from large Southwestern comprehensive cancer center were screened with the NCCN distress thermometer and FACT-BMT as part of routine care. Data were collected one day pre-transplant and 4-6 weeks post transplant. Data were analyzed using univariate and regression analyses. Results demonstrated that pre-transplant distress, while accounting for pre-transplant QOL was a significant predictor of post-transplant QOL (r = .242, p = .036). Fatigue was the most prevalent distressing problem both pre-transplant (54.4%) and post-transplant (57.9%). By conducting distress screening pre-transplantation, nurses may be better able to identify and manage distress earlier potentially improving patients’ overall quality of life (QOL).
Maryjo Prince-Paul, Dr. (Committee Chair)
Barbara Daly, Dr. (Committee Member)
Melanie Brewer, Dr. (Committee Member)
113 p.

Recommended Citations

Citations

  • Bautista, M. E. (2016). Distress and Quality of Life in Bone Marrow Transplant Patients [Doctoral dissertation, Case Western Reserve University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=casednp1460075757

    APA Style (7th edition)

  • Bautista, Maria. Distress and Quality of Life in Bone Marrow Transplant Patients. 2016. Case Western Reserve University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=casednp1460075757.

    MLA Style (8th edition)

  • Bautista, Maria. "Distress and Quality of Life in Bone Marrow Transplant Patients." Doctoral dissertation, Case Western Reserve University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=casednp1460075757

    Chicago Manual of Style (17th edition)