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Design and Synthesis of Superresolution Imaging Agents

Williams, Jarrod C.

Abstract Details

2012, PHD, Kent State University, College of Arts and Sciences / Department of Chemistry.
The field of superresolution imaging relies on techniques where the locations of sequential subsets of fluorophores are recorded and compiled in order to generate sub diffraction limited images. In order to ensure that only a few emitters are present within a diffraction limited volume, it is necessary to synthesize fluorophores whose emission can be controlled via photoactivation. We report the design and synthesis of a series of versatile azido DCDHF dyes, a class of photoactivatable fluorogens that are easily tailored to a wide variety of superresolution scenarios.
Robert Twieg (Advisor)
Paul Sampson (Committee Member)
Brett Ellman (Committee Member)
Scott Bunge (Committee Member)
Douglas Kline (Committee Member)
255 p.

Recommended Citations

Citations

  • Williams, J. C. (2012). Design and Synthesis of Superresolution Imaging Agents [Doctoral dissertation, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=kent1342887517

    APA Style (7th edition)

  • Williams, Jarrod. Design and Synthesis of Superresolution Imaging Agents. 2012. Kent State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=kent1342887517.

    MLA Style (8th edition)

  • Williams, Jarrod. "Design and Synthesis of Superresolution Imaging Agents." Doctoral dissertation, Kent State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=kent1342887517

    Chicago Manual of Style (17th edition)