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The Effect of High Intensity Exercise on pH and Inflammatory Biomarkers

Tyler, Alyssa N
http://rave.ohiolink.edu/etdc/view?acc_num=kent1405583783

Abstract Details

2014, MS, Kent State University, College of Education, Health and Human Services / School of Health Sciences.
High-intensity and prolonged duration of exercise has been found to inflict acute inflammation and localized muscle injury by releasing lactic acid and increasing plasma concentrations of both pro- and anti-inflammatory cytokines. Previous studies had used blood sample analysis to investigate this effect. The purpose of this research study was to examine the effect of high intensity exercise on the inflammatory biomarkers IL-6 and IL-1ß in male athletes using salivary analyses. A secondary purpose was to find a correlation between pH and each of the cytokines. Additionally, this study aimed to prove the accuracy of using saliva for inflammatory diagnosis in both current and future research studies. Nine conditioned male runners participated in an initial health questionnaire, a VO2max test, and a 60-minute run at 60% intensity, while maintaining at least 75% of their maximum heart rate. Saliva was collected at baseline, 30 min, 60 min, and 24 h post-trial run for the analysis of pH, IL-6, and IL-1ß. No significant increases of IL-6 and IL-1ß were observed. Additionally, there was no correlation found between pH and the biomarkers. The present study demonstrated an accuracy of using saliva for inflammatory diagnosis, producing a perfect standard curve and detectible data. The study also confirmed that the type of physical activity, frequency, duration, and intensity play a significant role in the acute inflammatory response.
Natalie Caine-Bish (Advisor)
Ellen Glickman (Committee Member)
Amy Miracle (Committee Member)
Curtis Fennell (Other)
Jennifer Marcinkiewicz (Other)
Health Sciences; Nutrition; Physiology
exercise; inflammation

Recommended Citations

Citations

  • Tyler, A. N. (2014). The Effect of High Intensity Exercise on pH and Inflammatory Biomarkers [Master's thesis, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=kent1405583783

    APA Style (7th edition)

  • Tyler, Alyssa. The Effect of High Intensity Exercise on pH and Inflammatory Biomarkers . 2014. Kent State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=kent1405583783.

    MLA Style (8th edition)

  • Tyler, Alyssa. "The Effect of High Intensity Exercise on pH and Inflammatory Biomarkers ." Master's thesis, Kent State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=kent1405583783

    Chicago Manual of Style (17th edition)

kent1405583783
13,227
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This open access ETD is published by Kent State University and OhioLINK.