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BIOMEDICAL APPLICATION OF THERMOCHROMIC LIQUID CRYSTALS AND LEUCO DYES FOR TEMPERATURE MONITORING IN THE EXTREMITIES

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2016, PHD, Kent State University, College of Education, Health and Human Services / School of Health Sciences.
ABSTRACT Nilin Rao, Ph.D., 2016 School of Health Sciences A Novel Thermochromic Liquid Crystal Fabric Design for the Early Detection of High-Risk Foot Complications: A Proof-of-Concept Study Director of Dissertation: Ellen Glickman, Ph.D. INTRODUCTION: We have developed a prototype of a novel thermochromic liquid crystal (TLC)-coated fabric with an extended temperature range and enhanced sensitivity. Employing both color and pattern recognition into the fabric, rapid determination of the underlying pedal temperature is facilitated. PURPOSE: The purpose of this study is to evaluate the accuracy of the fabric as a potential diagnostic aid for identifying complications in the high-risk foot. METHODS: The hands of one hundred subjects were used to compare the average maximum temperatures indicated by the fabric versus standard thermal camera images. Findings were statistically analyzed using a paired t-test with significance defined as p<0.05. RESULTS: With the exception of the tip of the thumb and regions in the palm, there were no significant differences between average maximum temperatures measured with the thermal camera and those detected with the TLC fabric. Minor differences were relatively consistent among all nine regions of the hand, and were not considered to be clinically significant. CONCLUSION: Using direct visual analysis, we were able to demonstrate that a novel TLC fabric was able to accurately map temperatures in the palmar surface of the hand. The findings support the continued development of a temperature-sensitive sock that can be used in home to monitor for temperature changes that may indicate the onset of high-risk foot complications.
Ellen Glickman, Ph.D. (Advisor)
Jacob Barkley, Ph.D. (Committee Member)
Jill Kawalec, Ph.D. (Committee Member)
Vincent Hetherington, DPM, M.S. (Committee Member)
Lawrence Osher, DPM (Committee Member)
82 p.

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Citations

  • Rao, N. M. (2016). BIOMEDICAL APPLICATION OF THERMOCHROMIC LIQUID CRYSTALS AND LEUCO DYES FOR TEMPERATURE MONITORING IN THE EXTREMITIES [Doctoral dissertation, Kent State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=kent1478957374245124

    APA Style (7th edition)

  • Rao, Nilin. BIOMEDICAL APPLICATION OF THERMOCHROMIC LIQUID CRYSTALS AND LEUCO DYES FOR TEMPERATURE MONITORING IN THE EXTREMITIES . 2016. Kent State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=kent1478957374245124.

    MLA Style (8th edition)

  • Rao, Nilin. "BIOMEDICAL APPLICATION OF THERMOCHROMIC LIQUID CRYSTALS AND LEUCO DYES FOR TEMPERATURE MONITORING IN THE EXTREMITIES ." Doctoral dissertation, Kent State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1478957374245124

    Chicago Manual of Style (17th edition)