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Novel Ex Vivo Ablation Test Model for Monopolar Hot Biopsy Forceps

Chen, Liang
http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1389353998

Abstract Details

2014, Master of Science (MS), Ohio University, Biomedical Engineering (Engineering and Technology).
Previous studies on hot biopsy forceps for colorectal polypectomy indicated that simulated ablation tests could provide useful information on hot biopsy forceps design and ablation parameter optimization that would help reducing the rate of potential polypectomy complications such as perforation. In this thesis, a novel ex vivo ablation test model for colonoscopic monopolar hot biopsy forceps was designed and implemented; simulated ablation tests had also been performed on this ablation test model for (a) verifying the model design and implementation, and (b) finding the roles of the major ablation parameters in tissue injury during the ablation process. In the design of this novel ex vivo ablation test model, a body equivalent block was introduced to simulate the properties of the human body. Porcine colon was used as tissue source for the simulated ablation tests. Major ablation parameters that were tested on this model covered (a) output power level, (b) firing duration, (c) contact area at the electrode tip, and (d) electrical impedance. Simulated ablation tests that were performed on this ablation test model covered the main combinations of targeted ablation parameters. During simulated ablation tests various ablation sites were generated under different parameter combinations, which indicated that this ablation test model can be used for hot biopsy forceps ablation studies. Some ablation parameters such as output power level and firing duration had dominating effects on the resulting ablation site geometry and tissue injury. The simulated test results showed the potential applications for testing hot biopsy forceps and optimizing ablation parameters.
JungHun Choi, PhD (Advisor)
Shiyong Wu, PhD (Committee Member)
Robert Williams, PhD (Committee Member)
John Cotton, PhD (Committee Member)
David Drozek, D.O (Committee Member)
106 p.
Biomedical Engineering; Biomedical Research
ex vivo; ablation; tissue injury; electrosurgical unit; ESU; impedence

Recommended Citations

Citations

  • Chen, L. (2014). Novel Ex Vivo Ablation Test Model for Monopolar Hot Biopsy Forceps [Master's thesis, Ohio University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1389353998

    APA Style (7th edition)

  • Chen, Liang. Novel Ex Vivo Ablation Test Model for Monopolar Hot Biopsy Forceps. 2014. Ohio University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1389353998.

    MLA Style (8th edition)

  • Chen, Liang. "Novel Ex Vivo Ablation Test Model for Monopolar Hot Biopsy Forceps." Master's thesis, Ohio University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1389353998

    Chicago Manual of Style (17th edition)

ohiou1389353998
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© 2013, all rights reserved.
This open access ETD is published by Ohio University and OhioLINK.