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osu1117578022.pdf (988.36 KB)
ETD Abstract Container
Abstract Header
Stress and immunity in a longitudinal study of breast cancer patients
Author Info
Thornton, Lisa Marie
Permalink:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1117578022
Abstract Details
Year and Degree
2005, Doctor of Philosophy, Ohio State University, Psychology.
Abstract
Previous research shows psychological stressors to correspond to decreased functioning of NK and T lymphocyte, immune cells which may affect cancer progression. Using data from a longitudinal study of breast cancer patients, we tested whether individual differences in level and change in the psychological stress response correspond to individual differences in level and change in NK and T lymphocyte function. Latent curve analyses suggested an inverse relationship between levels of T lymphocyte blastogenesis and levels of perceived stress and distress. This finding may indicate that stress and distress are related to T lymphocyte blastogenesis through consistent individual differences. Results also suggested an inverse relationship between change in perceived stress and change in NK lymphocyte function over the 18-month follow-up period. These data are consistent with the hypothesis that stressors affect immune function through psychological reactions to stress.
Committee
Barbara Andersen (Advisor)
Pages
167 p.
Subject Headings
Psychology, Clinical
Keywords
breast cancer
;
stress
;
immunity
;
latent curve analysis
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Citations
Thornton, L. M. (2005).
Stress and immunity in a longitudinal study of breast cancer patients
[Doctoral dissertation, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1117578022
APA Style (7th edition)
Thornton, Lisa.
Stress and immunity in a longitudinal study of breast cancer patients.
2005. Ohio State University, Doctoral dissertation.
OhioLINK Electronic Theses and Dissertations Center
, http://rave.ohiolink.edu/etdc/view?acc_num=osu1117578022.
MLA Style (8th edition)
Thornton, Lisa. "Stress and immunity in a longitudinal study of breast cancer patients." Doctoral dissertation, Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=osu1117578022
Chicago Manual of Style (17th edition)
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Document number:
osu1117578022
Download Count:
730
Copyright Info
© 2005, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.