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Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine Compared to 4% Articaine with 1:200,000 Epinephrine as Primary Buccal Infiltrations in Mandibular Posterior Teeth

McEntire, Mayes Allen
http://rave.ohiolink.edu/etdc/view?acc_num=osu1251743747

Abstract Details

2009, Master of Science, Ohio State University, Dentistry.
The purpose of this prospective, randomized, double-blind study was to compare the anesthetic efficacy of 1.8 mL of 4% articaine with 1:100,000 epinephrine to 1.8 mL 4% articaine with 1:200,000 epinephrine in mandibular buccal infiltration injections given next to the first molar. Using a cross-over design, 86 adult subjects (43 males and 43 females) randomly received two primary buccal mandibular infiltration injections given next to the first molar of 1.8 mL of 4% articaine with 1:100,000 epinephrine and 1.8 ml of 4% articaine with 1:200,000 epinephrine, in two separate appointments, spaced at least one week apart. The second molar through the first premolar were tested with an electric pulp tester every 3 minutes for a total of 60 minutes. The pain of injection and any postoperative discomfort over the next three days was rated by the subjects on a Heft-Parker visual analogue scale.Statistical analysis found no significant differences between the test solutions in frequency of pulpal anesthesia (80/80 readings) for any of the teeth tested. Anesthetic success was determined using three definitions of success. Success #1 was defined as achieving the first of two consecutive 80/80 readings by the third testing cycle (7 minutes for molars and 8 minutes for premolars) and maintaining the 80/80 readings throughout the testing period (60 minutes). Success #2 was defined as achieving the first of two consecutive 80/80 readings by the third testing cycle and sustaining this reading continuously for 60 minutes. This definition excluded subjects that experienced non-continuous anesthesia. Success #3 was defined as the occurrence of two consecutive 80/80 readings at any time during the testing period. There were no statistically significant differences between the two solutions using Success #1, Success #2 or Success #3 for any of the teeth tested. The two solutions showed no statistically significant differences for any tooth when comparing onset of pulpal anesthesia, failure, short duration of anesthesia, slow onset of anesthesia and non-continuous anesthesia. No significant difference in pain intensity existed between the two solutions for needle insertion, needle placement, or anesthetic deposition. Comparisons of mean post-operative pain ratings revealed no significant differences at the cessation of anesthesia or for any of the post-operative days.In conclusion, the anesthetic efficacy of 4% articaine with 1:200,000 epinephrine is comparable to 4% articaine with 1:100,000 epinephrine in a single primary mandibular buccal infiltration injection given next to the first molar.
John Nusstein (Advisor)
Al Reader (Committee Member)
Melissa Drum (Committee Member)
Michael Beck (Committee Member)
239 p.
Dental Care

Recommended Citations

Citations

  • McEntire, M. A. (2009). Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine Compared to 4% Articaine with 1:200,000 Epinephrine as Primary Buccal Infiltrations in Mandibular Posterior Teeth [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1251743747

    APA Style (7th edition)

  • McEntire, Mayes. Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine Compared to 4% Articaine with 1:200,000 Epinephrine as Primary Buccal Infiltrations in Mandibular Posterior Teeth. 2009. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1251743747.

    MLA Style (8th edition)

  • McEntire, Mayes. "Anesthetic Efficacy of 4% Articaine with 1:100,000 Epinephrine Compared to 4% Articaine with 1:200,000 Epinephrine as Primary Buccal Infiltrations in Mandibular Posterior Teeth." Master's thesis, Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1251743747

    Chicago Manual of Style (17th edition)

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This open access ETD is published by The Ohio State University and OhioLINK.