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The Effect of Preoperative Acetaminophen/Hydrocodone on the Efficacy of the Inferior Alveolar Nerve Block In Patients With Sypmtomatic Irreversible Pulpitis

Fullmer, Spencer C.
http://rave.ohiolink.edu/etdc/view?acc_num=osu1344539002

Abstract Details

2012, Master of Science, Ohio State University, Dentistry.
The inferior alveolar nerve block (IANB) is frequently used as a mandibular injection technique for achieving local anesthesia for endodontic treatment. Successful anesthesia, however, is not always achieved with the IANB. Studies have suggested that preoperative medications may increase the ability of clinicians to achieve profound pulpal anesthesia in conjunction with local anesthesia techniques. Acetaminophen/hydrocodone combination medications have been shown to effectively manage pain in a variety of dental pain models. The purpose of this prospective, randomized, double-blind, placebo-controlled study was to determine the effect of the administration of acetaminophen/hydrocodone on the efficacy of the IANB in patients with symptomatic irreversible pulpitis. One hundred emergency patients diagnosed with symptomatic irreversible pulpitis of a mandibular posterior tooth randomly received (in a double-blind manner) either four identical capsules of 10 mg hydrocodone and 1000 mg acetaminophen or a placebo 60 minutes before the administration of a conventional IANB. Fifteen minutes after administration of the IANB, profound lip numbness was confirmed, and endodontic access was initiated. Determination of success was, no or mild pain (less than or equal to 54 mm on a 170 mm visual analog scale) on access or instrumentation. The success rate for the IANB was 32% with the acetaminophen/hydrocodone group and 28% with the placebo group, with no significant difference (p = 0.66) between the groups. For mandibular posterior teeth, a preoperative dose of 10/1000 mg (hydrocodone/acetaminophen) did not result in a statistically significant increase of the success rate of the IAN block in patients with symptomatic irreversible pulpitis.
Melissa Drum, DDS MS (Advisor)
Alfred Reader, DDS MS (Committee Member)
John Nusstein, DDS MS (Committee Member)
Beck Frank, DDS MA (Committee Member)
144 p.
Biology; Dental Care; Medicine; Neurology; Neurosciences
inferior alveolar nerve block; acetaminophen; hydrocodone; preoperative; anesthesia; pulpitis

Recommended Citations

Citations

  • Fullmer, S. C. (2012). The Effect of Preoperative Acetaminophen/Hydrocodone on the Efficacy of the Inferior Alveolar Nerve Block In Patients With Sypmtomatic Irreversible Pulpitis [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1344539002

    APA Style (7th edition)

  • Fullmer, Spencer. The Effect of Preoperative Acetaminophen/Hydrocodone on the Efficacy of the Inferior Alveolar Nerve Block In Patients With Sypmtomatic Irreversible Pulpitis. 2012. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1344539002.

    MLA Style (8th edition)

  • Fullmer, Spencer. "The Effect of Preoperative Acetaminophen/Hydrocodone on the Efficacy of the Inferior Alveolar Nerve Block In Patients With Sypmtomatic Irreversible Pulpitis." Master's thesis, Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1344539002

    Chicago Manual of Style (17th edition)

osu1344539002
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© 2012, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.