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Gary Klase CPH thesis fixed.pdf (695.14 KB)

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The Chinese liver fluke Clonorchis sinensis: an environmental investigation into a foodborne parasite

Klase, Gary L
http://rave.ohiolink.edu/etdc/view?acc_num=osu1366378549

Abstract Details

2013, Master of Science, Ohio State University, Public Health.
The Chinese liver fluke Clonorchis sinensis is a foodborne parasitic trematode transmitted through the consumption of raw or undercooked fish, and is responsible for a substantial burden of morbidity and mortality in China and other Asian countries. The present study includes two investigations into environmental factors related to clonorchiasis transmission in China. In the first study, a field investigation was carried out in Guangdong province, China to investigate the relationship between water quality factors and the abundance and infection status of the snail intermediate of C. sinensis in rural Chinese fishponds. No host snails were found during the study. From the microbial source tracking analysis it was found that a large proportion of the water samples from fishponds showed evidence of human fecal contamination (84%), pig fecal contamination (40%), and antibiotic resistant bacteria (80%), raising concerns about potential public health risks related to these fishponds. In the second study, the results of a clonorchiasis prevalence study conducted by the Jiangmen City Center for Disease Control in Guangdong province were combined with satellite imagery and geographic information systems (GIS) techniques to investigate the relationship between the proportion of water in the nearby landscape and the risk of clonorchiasis infection. It was found that proximity to water in the landscape, as measured by the proportion of water in a 4 km radius around each village, was a strong risk factor for human infection of liver flukes. Using logistic regression, it was found that doubling the proportion of water around a village was associated with an odds ratio of 4.6 of increasing the liver fluke infection (p < 0.001).
Jiyoung Lee, Ph. D. (Advisor)
Song Liang, Ph. D. (Committee Member)
John Crawford, Ph. D. (Committee Member)
81 p.
Environmental Science; Fish Production; Geographic Information Science; Public Health
Clonorchis sinensis; clonorchiasis; ecological engineering; aquaculture; epidemiology; GIS

Recommended Citations

Citations

  • Klase, G. L. (2013). The Chinese liver fluke Clonorchis sinensis: an environmental investigation into a foodborne parasite [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1366378549

    APA Style (7th edition)

  • Klase, Gary. The Chinese liver fluke Clonorchis sinensis: an environmental investigation into a foodborne parasite. 2013. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1366378549.

    MLA Style (8th edition)

  • Klase, Gary. "The Chinese liver fluke Clonorchis sinensis: an environmental investigation into a foodborne parasite." Master's thesis, Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1366378549

    Chicago Manual of Style (17th edition)

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This open access ETD is published by The Ohio State University and OhioLINK.