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The Effect of Safflower oil-Containing Soy Snack Pretzels on Abdominal Obesity and Dietary Patterns in Overweight Postmenopausal Women with Metabolic Syndrome

Liu, Jingchen
http://orcid.org/0000-0002-9197-3945
http://rave.ohiolink.edu/etdc/view?acc_num=osu1429190003

Abstract Details

2015, Master of Science, Ohio State University, Allied Medical Professions.
Metabolic syndrome (MetS) refers to a cluster of interlinked components which interact with one another, resulting in elevated cardiovascular disease (CVD) risk and mortality. MetS has reached epidemic proportions with greater than 20% of the current US population affected. Post-menopausal women are at higher risk for both MetS and CVD, likely due to changes in sex hormones and altered fat distribution. Therapeutic lifestyle changes, including dietary interventions, remain optimal treatment for MetS. Previous studies document that high linoleic safflower oil supplementation promotes beneficial fat re-distribution, as well as anti-diabetic and anti-inflammatory qualities. Soy intake has been correlated with reductions in hyperglycemia and dyslipidemia. A randomized, 84-day, single-blind, cross-over pilot trial of 20 overweight postmenopausal women with or at high risk of MetS was designed to test the effectiveness of three types of functional snack pretzels on various metabolic parameters and changes in dietary patterns. Pretzels were isocaloric, and similar in macronutrient distribution. Daily consumption of 100 grams of prepackaged pretzel bites significantly decreased waist circumferences (116.94 ± 12.11 vs 113.49 ± 11.47 cm, p=0.013), mid-arm circumferences (39.65 ± 6.75 vs 38.61 ± 6.44 cm, p=0.005) and hip circumferences (126.68 ± 14.02 vs 125.23 ± 14.79 cm, p=0.041), with no significant changes in total body weight. Consumption of study pretzels also resulted in significantly decreased intake of dietary saturated fatty acids, trans fatty acids, and discretionary solid fat, which would further reduce CVD risks among this population. Despite instructions to maintain their usual diet, participants compensated for the added calories and refined grains from the study pretzels. These findings suggested that the functional snack pretzels can be incorporated in the dietary treatment of MetS among overweight postmenopausal women with MetS without negative changes to body composition. These findings will provide critical information needed for future large-scale dietary interventional trials involving functional snack foods as complementary or adjuvant therapy in this population.
Colleen Spees (Advisor)
Yael Vodovotz (Committee Member)
Martha Belury (Committee Member)
124 p.
Nutrition
Metabolic Syndrome, Functional foods, soy, safflower oil

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Citations

  • Liu, J. (2015). The Effect of Safflower oil-Containing Soy Snack Pretzels on Abdominal Obesity and Dietary Patterns in Overweight Postmenopausal Women with Metabolic Syndrome [Master's thesis, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429190003

    APA Style (7th edition)

  • Liu, Jingchen. The Effect of Safflower oil-Containing Soy Snack Pretzels on Abdominal Obesity and Dietary Patterns in Overweight Postmenopausal Women with Metabolic Syndrome. 2015. Ohio State University, Master's thesis. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1429190003.

    MLA Style (8th edition)

  • Liu, Jingchen. "The Effect of Safflower oil-Containing Soy Snack Pretzels on Abdominal Obesity and Dietary Patterns in Overweight Postmenopausal Women with Metabolic Syndrome." Master's thesis, Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1429190003

    Chicago Manual of Style (17th edition)

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This open access ETD is published by The Ohio State University and OhioLINK.