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Neuroplastic and Neuromuscular Effects of Knee Anterior Cruciate Ligament Injury

Grooms, Dustin R
http://orcid.org/0000-0001-6102-8224
http://rave.ohiolink.edu/etdc/view?acc_num=osu1437641044

Abstract Details

2015, Doctor of Philosophy, Ohio State University, Health and Rehabilitation Sciences.
Anterior cruciate ligament (ACL) ruptures are common activity-related knee injuries usually requiring surgical reconstruction and extensive rehabilitative therapy to restore knee stability and function. Despite surgical reconstruction and physical rehabilitation, injury of the ACL dramatically increases the risk for a second injury (re-tear or contralateral leg), costly and long-term disabling osteoarthritis as well as decreased lifelong physical activity. The mechanism of this injury is typically non-contact, meaning the individual experiences a loss of neuromuscular control during jump landing, running or a change of direction maneuver without contact from another person or any other external force. Current interventions focus on biomechanical adaptations, mitigating their effectiveness to address the full neuromuscular control system. In spite of the plethora of biomechanical and patient data collected over the last three decades, the re-injury rate has remained high, if returning to activity, and patient dysfunction remains prolonged. Previous investigators have observed central nervous system and somatosensory deficits despite ACL reconstruction and rehabilitation, and we suggest that this is likely due to a neuroplastic adaptation not currently understood. This project connects highly dynamic measures of knee neuromuscular function with whole brain activation patterns to generate a brain-behavior model. The integration of neuroimaging and biomechanics in this investigation identifies the central nervous system components of ACL injury not accounted for in current assessment and intervention techniques. Quantification of the underlying neurological changes that may be driving the biomechanical outcomes after ACL injury will allow neural correlates of function to be targeted in rehabilitation.
James Onate (Advisor)
Stephen Page (Committee Member)
Deborah Nichols-Larsen (Committee Member)
Ajit Chaudhari (Committee Member)
Susan White (Committee Member)
137 p.
Health Sciences; Neurosciences; Sports Medicine
Neuroimaging, Biomechanics, Sports medicine, Athletic training, fMRI, lower extremity

Recommended Citations

Citations

  • Grooms, D. R. (2015). Neuroplastic and Neuromuscular Effects of Knee Anterior Cruciate Ligament Injury [Doctoral dissertation, Ohio State University]. OhioLINK Electronic Theses and Dissertations Center. http://rave.ohiolink.edu/etdc/view?acc_num=osu1437641044

    APA Style (7th edition)

  • Grooms, Dustin. Neuroplastic and Neuromuscular Effects of Knee Anterior Cruciate Ligament Injury. 2015. Ohio State University, Doctoral dissertation. OhioLINK Electronic Theses and Dissertations Center, http://rave.ohiolink.edu/etdc/view?acc_num=osu1437641044.

    MLA Style (8th edition)

  • Grooms, Dustin. "Neuroplastic and Neuromuscular Effects of Knee Anterior Cruciate Ligament Injury." Doctoral dissertation, Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1437641044

    Chicago Manual of Style (17th edition)

osu1437641044
621
© 2015, all rights reserved.
This open access ETD is published by The Ohio State University and OhioLINK.